Objective To evaluate treatment adherence, survival and systemic patient and provider level factors associated with non-Hodgkin's lymphoma (NHL) management as reported by healthcare providers. Design Explanatory sequential mixed-methods study comprising a retrospective hospital-based cohort and a qualitative descriptive study.
Setting Felege Hiwot Comprehensive Specialized Hospital in Bahir Dar, Ethiopia, and the University of Gondar Comprehensive Specialized Hospital in Gondar, Ethiopia. Participants Adults (≥18 years) with histologically confirmed NHL who initiated systemic chemotherapy were eligible.
We randomly selected 182 patients with NHL treated and diagnosed between 1 August 2019 and 31 July 2024, for retrospective chart review out of a total of 283 patients during the study period. 14 healthcare professionals with at least 1 year of oncology experience participated in in-depth interviews.
Primary and secondary outcome The primary outcome was overall survival, defined as the time from histological diagnosis to death from any cause. The secondary outcome was treatment adherence, defined as interruption between cycles or abandonment of prescribed chemotherapy.
BMJ Open published a clinical update in Research Highlights on 11 May 2026.
The item focuses on Treatment adherence, survival outcomes and barriers to care of non-Hodgkin lymphoma in Northwest Ethiopia: a mixed-methods study.
Review the original article for the full source wording and details.