---
title: "Continuous Versus Intermittent Loop Diuretics in Acute Heart Failure: A Propensity-Matched Analy"
id: "journal-of-the-american-heart-association-80-continuous-versus-intermittent-loop-diuretics-step-by-step-protocol-in-acute-heart-failure-diur-ahf-a-propensity-matched-analysis"
canonical_url: "https://medichelpline.com/clinical-feed/journal-of-the-american-heart-association-80-continuous-versus-intermittent-loop-diuretics-step-by-step-protocol-in-acute-heart-failure-diur-ahf-a-propensity-matched-analysis"
content_type: "clinical_feed_article"
specialty: "Cardiology"
source_name: "Journal of the American Heart Association"
source_url: "https://www.ahajournals.org/doi/abs/10.1161/JAHA.125.045911?ai=sg&mi=3&af=R"
published_at: "2026-03-10T10:33:23.000Z"
evidence_level: "Journal Feed"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Continuous Versus Intermittent Loop Diuretics in Acute Heart Failure: A Propensity-Matched Analy
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/journal-of-the-american-heart-association-80-continuous-versus-intermittent-loop-diuretics-step-by-step-protocol-in-acute-heart-failure-diur-ahf-a-propensity-matched-analysis
- **Specialty:** [Cardiology](https://medichelpline.com/clinical-feed/cardiology.md)
- **Primary Source:** Journal of the American Heart Association
- **Source URL:** [Original Journal Publication](https://www.ahajournals.org/doi/abs/10.1161/JAHA.125.045911?ai=sg&mi=3&af=R)
- **Published At:** 2026-03-10T10:33:23.000Z
- **Evidence Rating:** Journal Feed
## Executive GIST (TL;DR)
Journal of the American Heart Association, Volume 15, Issue 6 , March 17, 2026. BackgroundLoop diuretics are used to solve congestion in acute heart failure. However, a clear indication about the best infusion modality, dose, and duration of the treatment has not yet been established. In this analysis of the DIUR‐AHF (Different Loop Diuretic Dosing and Administration in Acute Heart Failure) study, we aimed to investigate the effects of different diuretic administration modalities (ie, intermittent versus continuous furosemide infusion) and dose (high dose [HD] versus low dose) on congestion, renal function, and outcome.MethodsPatients received intermittent or continuous intravenous loop diuretics infusion combined as a 1:1 ratio for a period of 72 to 120 hours. HD was defined as a high loop diuretic dose >120 mg/d. Clinical outcome was evaluated in terms of death or heart failure rehospitalization over a 6‐month follow‐up period.ResultsA total of 370 patients with AHF were included in this analysis, 189 treated with continuous intravenous loop diuretics infusion and 181 with intermittent intravenous loop diuretics infusion.
## Clinical Analysis & Structured Key Points
Journal of the American Heart Association published a clinical update in Cardiology on 10 Mar 2026. The item focuses on Continuous Versus Intermittent Loop Diuretics Step‐by‐Step Protocol in Acute Heart Failure (DIUR‐AHF): A Propensity‐Matched Analysis. Review the original article for the full source wording and details.
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