---
title: "Age-Specific Excess Inpatient and ED Use Associated With Diabetes in the U.S."
id: "pubmed-42611023"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42611023"
content_type: "clinical_feed_article"
specialty: "Critical Care"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42611023/"
doi: "10.2337/dc26-0861"
published_at: "2026-08-18T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Age-Specific Excess Inpatient and ED Use Associated With Diabetes in the U.S.
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42611023
- **Specialty:** [Critical Care](https://medichelpline.com/clinical-feed/critical-care.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42611023/)
- **DOI:** [10.2337/dc26-0861](https://doi.org/10.2337%2Fdc26-0861)
- **Published At:** 2026-08-18T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- The study quantified national U.S. excess **inpatient admissions** and **emergency department (ED) visits** associated with **diabetes** across the adult age spectrum using 2019 data sources. - Data sources included the 2019 Behavioral Risk Factor Surveillance System, the National Inpatient Sample, and the Nationwide Emergency Department Sample to estimate events among adults with and without diabetes. - Complications were grouped as **traditional** diabetes complications (vascular and renal), **emerging** diabetes-associated conditions, or **other** co-occurring conditions. - The primary measure was age-standardized absolute risk differences (ARDs) comparing people with versus without diabetes to identify leading causes of excess hospital use by age and setting. - For inpatient admissions, traditional complications dominating excess burden were **sepsis**, **cardiorenal disease**, **acute kidney failure**, **myocardial infarction**, and **stroke**; reported ARDs ranged ~296 to 2,623 per 100,000 people with diabetes. - Emerging-condition drivers of excess use included **pneumonia**, device- and procedure-related complications (ARD range 125–473), and **schizoaffective/other mental health disorders** among younger adults (ARD range 80–312). - Other co-occurring conditions with notable excess burden across ages included **respiratory** and **fluid/electrolyte disorders** (ARD range 100–363); **digestive** and **urinary** disorders were more prominent in older adults (ARD range 229–482). - ED visits showed a broadly similar pattern of excess diagnoses but with lower ARDs compared with inpatient admissions (ARD range 101–707). - The authors conclude that diabetes drives substantial, age-specific excess inpatient and ED use and that nontraditional conditions increasingly contribute to this burden rather than only classic vascular and renal complications. - Funding sources included NIDDK grants listed in the article; the article was published online ahead of print in Diabetes Care (2026) with PMID 42611023 and DOI 10.2337/dc26-0861.
## Clinical Analysis & Structured Key Points
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Online ahead of print. # Excess Burden of Inpatient Admissions and Emergency Department Visits Associated With Diabetes Across the Age Spectrum [Rithik Patel](https://pubmed.ncbi.nlm.nih.gov/?term=Patel+R&cauthor_id=42611023)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-1 "Department of Surgery, Emory University School of Medicine, Atlanta, GA.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-2 "Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA."), [Tegveer S Uppal](https://pubmed.ncbi.nlm.nih.gov/?term=Uppal+TS&cauthor_id=42611023)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-3 "Emory Global Diabetes Research Center and Woodruff Health Sciences Center, Emory University, Atlanta, GA."), [Dunya Tomic](https://pubmed.ncbi.nlm.nih.gov/?term=Tomic+D&cauthor_id=42611023)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-4 "School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia."), [Mohammed K Ali](https://pubmed.ncbi.nlm.nih.gov/?term=Ali+MK&cauthor_id=42611023)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-3 "Emory Global Diabetes Research Center and Woodruff Health Sciences Center, Emory University, Atlanta, GA.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-5 "Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA."), [Agus Salim](https://pubmed.ncbi.nlm.nih.gov/?term=Salim+A&cauthor_id=42611023)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-4 "School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.")[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-6 "Diabetes and Population Health, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia."), [Dianna J Magliano](https://pubmed.ncbi.nlm.nih.gov/?term=Magliano+DJ&cauthor_id=42611023)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-4 "School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.")[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-6 "Diabetes and Population Health, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia."), [Jessica L Harding](https://pubmed.ncbi.nlm.nih.gov/?term=Harding+JL&cauthor_id=42611023)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-1 "Department of Surgery, Emory University School of Medicine, Atlanta, GA.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#full-view-affiliation-2 "Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.") Affiliations Expand ### Affiliations * 1 Department of Surgery, Emory University School of Medicine, Atlanta, GA. * 2 Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA. * 3 Emory Global Diabetes Research Center and Woodruff Health Sciences Center, Emory University, Atlanta, GA. * 4 School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. * 5 Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA. * 6 Diabetes and Population Health, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia. * PMID: **42611023** * DOI: [ 10.2337/dc26-0861 ](https://doi.org/10.2337/dc26-0861) Item in Clipboard # Excess Burden of Inpatient Admissions and Emergency Department Visits Associated With Diabetes Across the Age Spectrum Rithik Patel et al. Diabetes Care. 2026. Show details Display options Display options Format Abstract PubMed PMID Diabetes Care Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Diabetes+Care%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Diabetes+Care%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42611023/) . 2026 Aug 18:dc260861. doi: 10.2337/dc26-0861. Online ahead of print. ### Authors [Rithik Patel](https://pubmed.ncbi.nlm.nih.gov/?term=Patel+R&cauthor_id=42611023)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-1 "Department of Surgery, Emory University School of Medicine, Atlanta, GA.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-2 "Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA."), [Tegveer S Uppal](https://pubmed.ncbi.nlm.nih.gov/?term=Uppal+TS&cauthor_id=42611023)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-3 "Emory Global Diabetes Research Center and Woodruff Health Sciences Center, Emory University, Atlanta, GA."), [Dunya Tomic](https://pubmed.ncbi.nlm.nih.gov/?term=Tomic+D&cauthor_id=42611023)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-4 "School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia."), [Mohammed K Ali](https://pubmed.ncbi.nlm.nih.gov/?term=Ali+MK&cauthor_id=42611023)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-3 "Emory Global Diabetes Research Center and Woodruff Health Sciences Center, Emory University, Atlanta, GA.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-5 "Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA."), [Agus Salim](https://pubmed.ncbi.nlm.nih.gov/?term=Salim+A&cauthor_id=42611023)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-4 "School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.")[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-6 "Diabetes and Population Health, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia."), [Dianna J Magliano](https://pubmed.ncbi.nlm.nih.gov/?term=Magliano+DJ&cauthor_id=42611023)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-4 "School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.")[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-6 "Diabetes and Population Health, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia."), [Jessica L Harding](https://pubmed.ncbi.nlm.nih.gov/?term=Harding+JL&cauthor_id=42611023)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-1 "Department of Surgery, Emory University School of Medicine, Atlanta, GA.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42611023/#short-view-affiliation-2 "Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.") ### Affiliations * 1 Department of Surgery, Emory University School of Medicine, Atlanta, GA. * 2 Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA. * 3 Emory Global Diabetes Research Center and Woodruff Health Sciences Center, Emory University, Atlanta, GA. * 4 School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. * 5 Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA. * 6 Diabetes and Population Health, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia. * PMID: **42611023** * DOI: [ 10.2337/dc26-0861 ](https://doi.org/10.2337/dc26-0861) Item in Clipboard Cite Display options Display options Format Abstract PubMed PMID ## Abstract **Objective:** The epidemiology of diabetes and its complications is changing due to increasingly younger ages of diagnosis and increased life expectancy. How this changing landscape affects health care use, and for which conditions, is unclear. We examined age-specific excess burdens of cause-specific inpatient and emergency department (ED) visits associated with diabetes. **Research design and methods:** We used 2019 Behavioral Risk Factor Surveillance System, National Inpatient Sample, and Nationwide Emergency Department Sample data to derive national U.S. estimates of inpatient admissions and ED visits in adults with and without diabetes. Complications were categorized as traditional, conditions emerging as diabetes associated, or other conditions co-occurring with diabetes. We calculated age-standardized absolute risk differences (ARDs) in people with versus without diabetes to identify leading causes of diabetes-related hospital use by age and setting. **Results:** Traditional complications were dominated by sepsis, cardiorenal disease, acute kidney failure, myocardial infarction, and stroke, with ARDs ranging from 296 to 2,623 per 100,000 people with diabetes. Emerging conditions included pneumonia, device- and procedure-related complications (ARD range 125-473), and schizoaffective or other mental health disorders in younger adults only (ARD range 80-312). Other conditions included respiratory and fluid/electrolyte disorders across all ages (ARD range 100-363), while digestive and urinary disorders were more prominent in older adults (ARD range 229-482). ED visits showed a similar pattern, with lower ARD than inpatient admissions (ARD range 101-707). **Conclusions:** Diabetes drives substantial, age-specific excess inpatient and ED use, increasingly due to nontraditional rather than classic vascular and renal complications. © 2026 by the American Diabetes Association. 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