---
title: "Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial"
id: "clinicaltrials-nct06337838"
canonical_url: "https://medichelpline.com/clinical-feed/clinicaltrials-nct06337838"
content_type: "clinical_feed_article"
specialty: "Critical Care"
source_name: "ClinicalTrials.gov"
source_url: "https://clinicaltrials.gov/study/NCT06337838"
doi: "NCT06337838"
published_at: "2026-03-24T12:00:00.000Z"
evidence_level: "INTERVENTIONAL Trial"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/clinicaltrials-nct06337838
- **Specialty:** [Critical Care](https://medichelpline.com/clinical-feed/critical-care.md)
- **Primary Source:** ClinicalTrials.gov
- **Source URL:** [Original Journal Publication](https://clinicaltrials.gov/study/NCT06337838)
- **DOI:** [NCT06337838](https://doi.org/NCT06337838)
- **Published At:** 2026-03-24T12:00:00.000Z
- **Evidence Rating:** INTERVENTIONAL Trial
## Executive GIST (TL;DR)
RECRUITING · INTERVENTIONAL · TREATMENT study · Chronic Kidney Diseases · Phase 3 · Enrollment 100 · Sponsor: Hamilton Health Sciences Corporation
## Clinical Analysis & Structured Key Points
Official title: Bleeding Reduction in Acute and Chronic KidnEy patienTs Having Surgery (BRACKETS) Pilot Trial Summary: The BRACKETS pilot study is a multicentre, prospective, randomized controlled trial of prophylactic preoperative tranexamic acid (TXA) versus placebo and, using a partial factorial design, of prophylactic preoperative desmopressin versus placebo. Conditions: Chronic Kidney Diseases, Acute Kidney Injury, Bleeding, Surgery Keywords: Major Noncardiac Surgery, Tranexamic Acid, Desmopressin Study type: INTERVENTIONAL Primary purpose: TREATMENT Phases: PHASE3 Enrollment: 100 (ESTIMATED) Status: RECRUITING Completion: 2027-06 (ESTIMATED)
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