---
title: "Fluid Resuscitation in Sepsis: NEJM Editorial and Publication Details"
id: "pubmed-42685324"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42685324"
content_type: "clinical_feed_article"
specialty: "Critical Care"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42685324/"
doi: "10.1056/NEJMe2609856"
published_at: "2026-09-03T00:00:00.000Z"
evidence_level: "Editorial"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Fluid Resuscitation in Sepsis: NEJM Editorial and Publication Details
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42685324
- **Specialty:** [Critical Care](https://medichelpline.com/clinical-feed/critical-care.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42685324/)
- **DOI:** [10.1056/NEJMe2609856](https://doi.org/10.1056%2FNEJMe2609856)
- **Published At:** 2026-09-03T00:00:00.000Z
- **Evidence Rating:** Editorial
## Executive GIST (TL;DR)
- This PubMed entry is for an editorial titled “Fluid Resuscitation in Patients with Sepsis - For Whom the Balance Tolls” appearing in the New England Journal of Medicine (N Engl J Med) on 2026 Sep 3, volume 395, pages 921–922. - Authors listed are Michael F. O'Connor (Department of Anesthesia and Critical Care, University of Chicago) and Juliane Bubeck-Wardenburg (Department of Pediatrics, Washington University School of Medicine, St. Louis). - The citation includes DOI 10.1056/NEJMe2609856 and PubMed ID (PMID) 42685324. - The PubMed record classifies the item as an **Editorial** and provides bibliographic metadata but states “No abstract available.” - The article title indicates the topic relates to **fluid resuscitation** in patients with **sepsis**, but the PubMed record does not include the editorial text or an abstract to summarize conclusions, recommendations, or data. - Affiliation details for the two authors are provided in the record; institutional and departmental information is explicitly listed for both. - The PubMed page provides standard site indicators (secure site, .gov domain) and standard PubMed navigation and export tools (save, email, citation formats), but the record does not contain the article body or a summary of clinical content. - For clinicians or researchers seeking the full editorial content or clinical arguments, the DOI and journal citation are provided for locating the original NEJM issue; however, access to full text may require journal subscription or institutional access. - Any clinical assertions, recommendations, study outcomes, or detailed analyses are not available in the PubMed record and are therefore not reported here.
## Clinical Analysis & Structured Key Points
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Affiliations Expand ### Affiliations * 1 Department of Anesthesia and Critical Care, University of Chicago, Chicago. * 2 Department of Pediatrics, Washington University School of Medicine, St. Louis. * PMID: **42685324** * DOI: [ 10.1056/NEJMe2609856 ](https://doi.org/10.1056/nejme2609856) Item in Clipboard Editorial # Fluid Resuscitation in Patients with Sepsis - For Whom the Balance Tolls Michael F O'Connor et al. N Engl J Med. 2026. Show details Display options Display options Format Abstract PubMed PMID N Engl J Med Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22N+Engl+J+Med%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22N+Engl+J+Med%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42685324/) . 2026 Sep 3;395(9):921-922. doi: 10.1056/NEJMe2609856. ### Authors [Michael F O'Connor](https://pubmed.ncbi.nlm.nih.gov/?term=O%27Connor+MF&cauthor_id=42685324)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42685324/#short-view-affiliation-1 "Department of Anesthesia and Critical Care, University of Chicago, Chicago."), [Juliane Bubeck-Wardenburg](https://pubmed.ncbi.nlm.nih.gov/?term=Bubeck-Wardenburg+J&cauthor_id=42685324)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42685324/#short-view-affiliation-2 "Department of Pediatrics, Washington University School of Medicine, St. Louis.") ### Affiliations * 1 Department of Anesthesia and Critical Care, University of Chicago, Chicago. * 2 Department of Pediatrics, Washington University School of Medicine, St. Louis. * PMID: **42685324** * DOI: [ 10.1056/NEJMe2609856 ](https://doi.org/10.1056/nejme2609856) Item in Clipboard Cite Display options Display options Format Abstract PubMed PMID _No abstract available_ [PubMed Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) ## Publication types * Editorial Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Editorial%22%5Bpt%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Editorial) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42685324/) [x] Cite Copy Download .nbib .nbib Format: AMA APA MLA NLM **Send To** * [Clipboard](https://pubmed.ncbi.nlm.nih.gov/42685324/) * [Email](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42685324%2F%23open-email-panel) * [Save](https://pubmed.ncbi.nlm.nih.gov/42685324/) * [My Bibliography](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42685324%2F%23open-bibliography-panel) * [Collections](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42685324%2F%23open-collections-panel) * [Citation Manager](https://pubmed.ncbi.nlm.nih.gov/42685324/) [x] NCBI Literature Resources [MeSH](https://www.ncbi.nlm.nih.gov/mesh/) [PMC](https://www.ncbi.nlm.nih.gov/pmc/) [Bookshelf](https://www.ncbi.nlm.nih.gov/books) [Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 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