---
title: "GINA 2026 Update: Focus on Asthma-Related Cough and Diagnostic Guidance"
id: "pubmed-42706200"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42706200"
content_type: "clinical_feed_article"
specialty: "Critical Care"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42706200/"
doi: "10.3760/cma.j.cn112147-20260514-00275"
published_at: "2026-09-12T00:00:00.000Z"
evidence_level: "English Abstract"
license: "CC-BY-NC-4.0 / Informational Use"
---
# GINA 2026 Update: Focus on Asthma-Related Cough and Diagnostic Guidance
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42706200
- **Specialty:** [Critical Care](https://medichelpline.com/clinical-feed/critical-care.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42706200/)
- **DOI:** [10.3760/cma.j.cn112147-20260514-00275](https://doi.org/10.3760%2Fcma.j.cn112147-20260514-00275)
- **Published At:** 2026-09-12T00:00:00.000Z
- **Evidence Rating:** English Abstract
## Executive GIST (TL;DR)
- The GINA 2026 update increases emphasis on **asthma-related cough** across diagnosis, differential diagnosis, and assessment. - Key changes include refinement of **cough-related asthma phenotypes**, indicating more granular categorization of cough presentations in asthma. - The update adds **induced sputum differential cell** analysis as a diagnostic tool for asthma, expanding objective testing options. - **Chronic cough–related etiologies** are now explicitly included in the differential diagnosis of asthma, encouraging clinicians to consider nonasthma causes when cough predominates. - **Cough symptoms** have been integrated into routine asthma assessment, reflecting their clinical importance for control and evaluation. - The expanded coverage of cough in GINA 2026 signals growing global attention to cough in asthma management. - The update also highlights GINA’s acknowledgment of research contributions from China in the area of asthma-related cough. - The article reporting these changes lists authors K F Lai and F Yi, is published in Zhonghua Jie He He Hu Xi Za Zhi (2026 Sep 12;49(9):921-923), and declares no conflicts of interest.
## Clinical Analysis & Structured Key Points
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Affiliations Expand ### Affiliation * 1 Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China. * PMID: **42706200** * DOI: [ 10.3760/cma.j.cn112147-20260514-00275 ](https://doi.org/10.3760/cma.j.cn112147-20260514-00275) Item in Clipboard # [Global initiative for asthma (GINA) 2026 update: persistent attention to asthma-related cough] [Article in Chinese] K F Lai et al. Zhonghua Jie He He Hu Xi Za Zhi. 2026. Show details Display options Display options Format Abstract PubMed PMID Zhonghua Jie He He Hu Xi Za Zhi Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Zhonghua+Jie+He+He+Hu+Xi+Za+Zhi%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Zhonghua+Jie+He+He+Hu+Xi+Za+Zhi%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42706200/) . 2026 Sep 12;49(9):921-923. doi: 10.3760/cma.j.cn112147-20260514-00275. ### Authors [K F Lai](https://pubmed.ncbi.nlm.nih.gov/?term=Lai+KF&cauthor_id=42706200)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42706200/#short-view-affiliation-1 "Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China."), [F Yi](https://pubmed.ncbi.nlm.nih.gov/?term=Yi+F&cauthor_id=42706200)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42706200/#short-view-affiliation-1 "Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.") ### Affiliation * 1 Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China. * PMID: **42706200** * DOI: [ 10.3760/cma.j.cn112147-20260514-00275 ](https://doi.org/10.3760/cma.j.cn112147-20260514-00275) Item in Clipboard Full text links Cite Display options Display options Format Abstract PubMed PMID ## Abstract in [ English, ](https://pubmed.ncbi.nlm.nih.gov/42706200/#eng-abstract) [ Chinese ](https://pubmed.ncbi.nlm.nih.gov/42706200/#zho-abstract) The 2026 update of the Global Initiative for Asthma (GINA) further strengthens cough-related content in the diagnosis, differential diagnosis, and assessment of asthma. The major updates include refinement of cough-related asthma phenotypes, incorporation of induced sputum differential cell as a diagnostic method for asthma, inclusion of chronic cough-related etiologies in the differential diagnosis of asthma, and the integration of cough symptoms into asthma assessment. The expanded coverage of cough in the GINA 2026 update reflects the growing global attention to cough in asthma, and also highlights GINA's acknowledgment of research achievements from China in this field. 全球哮喘防治创议（GINA）2026更新版在哮喘诊断、鉴别诊断及评估等方面进一步强化了咳嗽相关内容，主要包括哮喘相关咳嗽表型的细化、新增诱导痰细胞学检查作为哮喘诊断手段、将慢性咳嗽相关病因纳入哮喘鉴别诊断、将咳嗽症状纳入哮喘的评估。GINA 2026更新版指南对哮喘相关咳嗽内容的拓展，既反映了全球哮喘学界对哮喘相关咳嗽问题的重视，也体现了GINA对中国哮喘相关咳嗽研究成果的认可。. [PubMed Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) ## Conflict of interest statement 所有作者声明无利益冲突 ## Similar articles * [ The relationship between psychogenic cough and the diagnosis and misdiagnosis of asthma: a review. ](https://pubmed.ncbi.nlm.nih.gov/17613629/) Linz AJ.Linz AJ.J Asthma. 2007 Jun;44(5):347-55. doi: 10.1080/02770900701344330.J Asthma. 2007.PMID: 17613629Review. * [ Objective Cough Frequency, Airway Inflammation, and Disease Control in Asthma. ](https://pubmed.ncbi.nlm.nih.gov/26973014/) Marsden PA, Satia I, Ibrahim B, Woodcock A, Yates L, Donnelly I, Jolly L, Thomson NC, Fowler SJ, Smith JA.Marsden PA, et al.Chest. 2016 Jun;149(6):1460-6. doi: 10.1016/j.chest.2016.02.676. Epub 2016 Mar 10.Chest. 2016.PMID: 26973014 * [ The Pulmonologist's Approach to the Diagnosis and Treatment of Cough. ](https://pubmed.ncbi.nlm.nih.gov/42161710/) Posner D.Posner D.Otolaryngol Clin North Am. 2026 Aug;59(4):781-790. doi: 10.1016/j.otc.2026.04.005. 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