---
title: "Lancet Commission on Sepsis: metadata, authors, and conflict-of-interest summary"
id: "pubmed-42034118"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42034118"
content_type: "clinical_feed_article"
specialty: "Critical Care"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42034118/"
doi: "10.1016/S0140-6736(26)00648-3"
published_at: "2026-10-10T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Lancet Commission on Sepsis: metadata, authors, and conflict-of-interest summary
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42034118
- **Specialty:** [Critical Care](https://medichelpline.com/clinical-feed/critical-care.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42034118/)
- **DOI:** [10.1016/S0140-6736(26)00648-3](https://doi.org/10.1016%2FS0140-6736(26)00648-3)
- **Published At:** 2026-10-10T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- The source is a Lancet Commission piece titled “The Lancet Commission on Sepsis: transforming sepsis care and outcomes,” indexed in PubMed with PMID **42034118** and DOI **10.1016/S0140-6736(26)00648-3**. The article is cited as Lancet. 2026 Oct 10;408(10563):1406-1408 and was published online 22 April 2026. - No abstract is available in the PubMed entry; the PubMed record provides title, author list, affiliations, publication details, and a conflict-of-interest statement only. - The author group is multidisciplinary and international; named lead authors include Manu Shankar-Hari, Damien Ming, Marc Mendelson, Priscilla Rupali, Neill K J Adhikari, Otavio Ranzani, Adrienne Randolph, Emma Davenport, Tom van der Poll, Luis Ferreira Moita, Abi Beane, Francois Lamontagne, Arthur Kwizera, Alison Holmes, and Janet Diaz. - Affiliations span academic and clinical centres in the UK, South Africa, India, Canada, Spain, the USA, the Netherlands, Portugal, Uganda, and the World Health Organization. - The PubMed entry lists a detailed conflict-of-interest statement for multiple authors, reporting funding sources, awards, consulting, royalties, participation on DSMBs, and memberships in sepsis-related organisations. Specific disclosures are reported for MS-H, DM, NKJA, OR, AR and others as provided in the record. - The PubMed record includes standard navigation and site UI text but contains no study methods, results, recommendations, or other content beyond bibliographic and COI information. - Because the PubMed entry contains no abstract or article text, clinical content, recommendations, and commission conclusions are not reported in this source and therefore are not summarized here.
## Clinical Analysis & Structured Key Points
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Epub 2026 Apr 22. # The Lancet Commission on Sepsis: transforming sepsis care and outcomes [Manu Shankar-Hari](https://pubmed.ncbi.nlm.nih.gov/?term=Shankar-Hari+M&cauthor_id=42034118)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-1 "Centre for Critical Illness Research, Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London SE1 9RT, UK. Electronic address: manu.shankar-hari@kcl.ac.uk."), [Damien Ming](https://pubmed.ncbi.nlm.nih.gov/?term=Ming+D&cauthor_id=42034118)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-2 "The Fleming Initiative, Imperial College London, London, UK."), [Marc Mendelson](https://pubmed.ncbi.nlm.nih.gov/?term=Mendelson+M&cauthor_id=42034118)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-3 "Division of Infectious Diseases and HIV Medicine, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa."), [Priscilla Rupali](https://pubmed.ncbi.nlm.nih.gov/?term=Rupali+P&cauthor_id=42034118)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-4 "Department of Infectious Diseases, Christian Medical College, Vellore, India."), [Neill K J Adhikari](https://pubmed.ncbi.nlm.nih.gov/?term=Adhikari+NKJ&cauthor_id=42034118)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-5 "Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada."), [Otavio Ranzani](https://pubmed.ncbi.nlm.nih.gov/?term=Ranzani+O&cauthor_id=42034118)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-6 "DataHealth Lab, Institut de Recerca Sant Pau \(IR SANT PAU\), Barcelona, Spain."), [Adrienne Randolph](https://pubmed.ncbi.nlm.nih.gov/?term=Randolph+A&cauthor_id=42034118)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-7 "Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA."), [Emma Davenport](https://pubmed.ncbi.nlm.nih.gov/?term=Davenport+E&cauthor_id=42034118)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-8 "Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK."), [Tom van der Poll](https://pubmed.ncbi.nlm.nih.gov/?term=van+der+Poll+T&cauthor_id=42034118)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-9 "Amsterdam UMC, University of Amsterdam, Center for Infection and Molecular Medicine & Division of Infectious Diseases, Amsterdam, Netherlands."), [Luis Ferreira Moita](https://pubmed.ncbi.nlm.nih.gov/?term=Moita+LF&cauthor_id=42034118)[ 10 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-10 "Center for Disease Mechanisms Research, Medicine ULisboa for Health Clinical Research and Innovation \(MUHCRI\), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal."), [Abi Beane](https://pubmed.ncbi.nlm.nih.gov/?term=Beane+A&cauthor_id=42034118)[ 11 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-11 "Pandemic Sciences Hub and Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK."), [Francois Lamontagne](https://pubmed.ncbi.nlm.nih.gov/?term=Lamontagne+F&cauthor_id=42034118)[ 12 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-12 "Université de Sherbrooke, Sherbrooke, QC, Canada."), [Arthur Kwizera](https://pubmed.ncbi.nlm.nih.gov/?term=Kwizera+A&cauthor_id=42034118)[ 13 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-13 "Makerere University College of Health Sciences, Kampala, Uganda."), [Alison Holmes](https://pubmed.ncbi.nlm.nih.gov/?term=Holmes+A&cauthor_id=42034118)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-2 "The Fleming Initiative, Imperial College London, London, UK."), [Janet Diaz](https://pubmed.ncbi.nlm.nih.gov/?term=Diaz+J&cauthor_id=42034118)[ 14 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#full-view-affiliation-14 "Clinical Management and Operations Unit, World Health Organization, Geneva, Switzerland.") Affiliations Expand ### Affiliations * 1 Centre for Critical Illness Research, Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London SE1 9RT, UK. Electronic address: manu.shankar-hari@kcl.ac.uk. * 2 The Fleming Initiative, Imperial College London, London, UK. * 3 Division of Infectious Diseases and HIV Medicine, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa. * 4 Department of Infectious Diseases, Christian Medical College, Vellore, India. * 5 Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. * 6 DataHealth Lab, Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Spain. * 7 Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA. * 8 Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. * 9 Amsterdam UMC, University of Amsterdam, Center for Infection and Molecular Medicine & Division of Infectious Diseases, Amsterdam, Netherlands. * 10 Center for Disease Mechanisms Research, Medicine ULisboa for Health Clinical Research and Innovation (MUHCRI), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal. * 11 Pandemic Sciences Hub and Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK. * 12 Université de Sherbrooke, Sherbrooke, QC, Canada. * 13 Makerere University College of Health Sciences, Kampala, Uganda. * 14 Clinical Management and Operations Unit, World Health Organization, Geneva, Switzerland. * PMID: **42034118** * DOI: [ 10.1016/S0140-6736(26)00648-3 ](https://doi.org/10.1016/s0140-6736\(26\)00648-3) Item in Clipboard # The Lancet Commission on Sepsis: transforming sepsis care and outcomes Manu Shankar-Hari et al. Lancet. 2026. Show details Display options Display options Format Abstract PubMed PMID Lancet Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Lancet%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Lancet%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42034118/) . 2026 Oct 10;408(10563):1406-1408. doi: 10.1016/S0140-6736(26)00648-3. Epub 2026 Apr 22. ### Authors [Manu Shankar-Hari](https://pubmed.ncbi.nlm.nih.gov/?term=Shankar-Hari+M&cauthor_id=42034118)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-1 "Centre for Critical Illness Research, Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London SE1 9RT, UK. Electronic address: manu.shankar-hari@kcl.ac.uk."), [Damien Ming](https://pubmed.ncbi.nlm.nih.gov/?term=Ming+D&cauthor_id=42034118)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-2 "The Fleming Initiative, Imperial College London, London, UK."), [Marc Mendelson](https://pubmed.ncbi.nlm.nih.gov/?term=Mendelson+M&cauthor_id=42034118)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-3 "Division of Infectious Diseases and HIV Medicine, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa."), [Priscilla Rupali](https://pubmed.ncbi.nlm.nih.gov/?term=Rupali+P&cauthor_id=42034118)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-4 "Department of Infectious Diseases, Christian Medical College, Vellore, India."), [Neill K J Adhikari](https://pubmed.ncbi.nlm.nih.gov/?term=Adhikari+NKJ&cauthor_id=42034118)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-5 "Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada."), [Otavio Ranzani](https://pubmed.ncbi.nlm.nih.gov/?term=Ranzani+O&cauthor_id=42034118)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-6 "DataHealth Lab, Institut de Recerca Sant Pau \(IR SANT PAU\), Barcelona, Spain."), [Adrienne Randolph](https://pubmed.ncbi.nlm.nih.gov/?term=Randolph+A&cauthor_id=42034118)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-7 "Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA."), [Emma Davenport](https://pubmed.ncbi.nlm.nih.gov/?term=Davenport+E&cauthor_id=42034118)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-8 "Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK."), [Tom van der Poll](https://pubmed.ncbi.nlm.nih.gov/?term=van+der+Poll+T&cauthor_id=42034118)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-9 "Amsterdam UMC, University of Amsterdam, Center for Infection and Molecular Medicine & Division of Infectious Diseases, Amsterdam, Netherlands."), [Luis Ferreira Moita](https://pubmed.ncbi.nlm.nih.gov/?term=Moita+LF&cauthor_id=42034118)[ 10 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-10 "Center for Disease Mechanisms Research, Medicine ULisboa for Health Clinical Research and Innovation \(MUHCRI\), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal."), [Abi Beane](https://pubmed.ncbi.nlm.nih.gov/?term=Beane+A&cauthor_id=42034118)[ 11 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-11 "Pandemic Sciences Hub and Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK."), [Francois Lamontagne](https://pubmed.ncbi.nlm.nih.gov/?term=Lamontagne+F&cauthor_id=42034118)[ 12 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-12 "Université de Sherbrooke, Sherbrooke, QC, Canada."), [Arthur Kwizera](https://pubmed.ncbi.nlm.nih.gov/?term=Kwizera+A&cauthor_id=42034118)[ 13 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-13 "Makerere University College of Health Sciences, Kampala, Uganda."), [Alison Holmes](https://pubmed.ncbi.nlm.nih.gov/?term=Holmes+A&cauthor_id=42034118)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-2 "The Fleming Initiative, Imperial College London, London, UK."), [Janet Diaz](https://pubmed.ncbi.nlm.nih.gov/?term=Diaz+J&cauthor_id=42034118)[ 14 ](https://pubmed.ncbi.nlm.nih.gov/42034118/#short-view-affiliation-14 "Clinical Management and Operations Unit, World Health Organization, Geneva, Switzerland.") ### Affiliations * 1 Centre for Critical Illness Research, Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London SE1 9RT, UK. Electronic address: manu.shankar-hari@kcl.ac.uk. * 2 The Fleming Initiative, Imperial College London, London, UK. * 3 Division of Infectious Diseases and HIV Medicine, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa. * 4 Department of Infectious Diseases, Christian Medical College, Vellore, India. * 5 Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. * 6 DataHealth Lab, Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Spain. * 7 Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA. * 8 Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. * 9 Amsterdam UMC, University of Amsterdam, Center for Infection and Molecular Medicine & Division of Infectious Diseases, Amsterdam, Netherlands. * 10 Center for Disease Mechanisms Research, Medicine ULisboa for Health Clinical Research and Innovation (MUHCRI), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal. * 11 Pandemic Sciences Hub and Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, UK. * 12 Université de Sherbrooke, Sherbrooke, QC, Canada. * 13 Makerere University College of Health Sciences, Kampala, Uganda. * 14 Clinical Management and Operations Unit, World Health Organization, Geneva, Switzerland. * PMID: **42034118** * DOI: [ 10.1016/S0140-6736(26)00648-3 ](https://doi.org/10.1016/s0140-6736\(26\)00648-3) Item in Clipboard Cite Display options Display options Format Abstract PubMed PMID _No abstract available_ [PubMed Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) ## Conflict of interest statement MS-H reports an NIHR Clinician Scientist Award (NIHR-CS-2016-16-011) from the UK National Institute for Health and Care Research (NIHR), is a member of the MRC/NIHR EME Programme, Chair of the EME-NIHR Advanced Fellowship Committee, Council of International Sepsis Forum, receives funding for his research from the NIHR, Wellcome Trust, the Medical Research Council, and Chief Scientist's Office Scotland, and has done advisory board activity through the International Sepsis Forum with payments going either into the unrestricted institutional research funds or to the International Sepsis Forum. DM reports research grants from LifeArc and NIHR. NKJA reports grants from the Canadian Institutes of Health Research (CIHR) with payments made to their institution. OR is funded by the Ramón y Cajal Programme (RYC2023-002923-C) awarded by the Spanish Ministry of Science, Innovation and Universities. AR reports grants from the US Centers for Disease Control and Prevention and National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases, receives royalties from UpToDate, consulting fees from Inotrem, honoraria for talks from ThermoFisher, reports participation on a Data Safety Monitoring Board (DSMB) for the REMAP-CAP and Prevent VILI trials, and is a Council member of the International Sepsis Forum and a Medical Advisory Board member of the Families Fighting Flu char
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