---
title: "Microsurgical versus conventional surgery for gingival recession with collagen matrix: randomized"
id: "pubmed-42664116"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42664116"
content_type: "clinical_feed_article"
specialty: "Dentistry"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42664116/"
doi: "10.7417/CT.2026.2096"
published_at: "2026-09-01T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Microsurgical versus conventional surgery for gingival recession with collagen matrix: randomized
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42664116
- **Specialty:** [Dentistry](https://medichelpline.com/clinical-feed/dentistry.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42664116/)
- **DOI:** [10.7417/CT.2026.2096](https://doi.org/10.7417%2FCT.2026.2096)
- **Published At:** 2026-09-01T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- This randomized split-mouth clinical trial compared **microsurgery** (3.5X magnification) with **conventional surgery** for treating gingival recession using a **collagen matrix**. - Study population: 29 patients with bilateral gingival recession in the maxillary canine and/or premolar region; sites randomized to test (microsurgery) or control (conventional surgery). - Clinical and patient-reported outcomes were recorded at baseline, 1, 3 and 6 months. - Both groups achieved statistically significant improvements at 6 months in gingival recession height (GRH), gingival recession width (GRW), clinical attachment level gain (CAL gain), keratinized tissue thickness (KTT) and keratinized tissue width (KTW). - Intergroup comparisons of clinical parameters showed no significant differences between microsurgical and conventional approaches. - Patient-centred outcomes (patient satisfaction score, hypersensitivity score, root aesthetic scores) were significantly better with the **microsurgical** approach. - Authors conclude both techniques provide comparable clinical improvement, but the **microsurgical** approach produced superior patient-reported outcomes; choice of technique should balance patient needs with cost, time, and clinician expertise. - Trial published by Perambudhuru et al., Clin Ter. 2026; affiliations include the Division of Periodontology and Department of Anatomy at All India Institute of Medical Sciences (AIIMS) Bathinda and AIIMS Delhi. PMID: 42664116.
## Clinical Analysis & Structured Key Points
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Affiliations Expand ### Affiliations * 1 Division of Periodontology, Department of Dentistry, All India Institute of Medical Sciences, Bathinda, India. * 2 Department of Anatomy, All India Institute of Medical Sciences, Bathinda. * 3 Division of Periodontics, Centre of Dental Education and Research, All India Institute of Medical Sciences, Delhi, India. * PMID: **42664116** * DOI: [ 10.7417/CT.2026.2096 ](https://doi.org/10.7417/ct.2026.2096) Free article Item in Clipboard Clinical Trial # Comparison of conventional and micro-surgical techniques for gingival recession using collagen matrix: Randomised controlled split-mouth clinical trial Yeshwanth Perambudhuru et al. Clin Ter. 2026 Sep-Oct. Free article Show details Display options Display options Format Abstract PubMed PMID Clin Ter Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Clin+Ter%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Clin+Ter%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) . 2026 Sep-Oct;177(5):992-1000. doi: 10.7417/CT.2026.2096. ### Authors [Yeshwanth Perambudhuru](https://pubmed.ncbi.nlm.nih.gov/?term=Perambudhuru+Y&cauthor_id=42664116)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42664116/#short-view-affiliation-1 "Division of Periodontology, Department of Dentistry, All India Institute of Medical Sciences, Bathinda, India."), [Lata Goyal](https://pubmed.ncbi.nlm.nih.gov/?term=Goyal+L&cauthor_id=42664116)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42664116/#short-view-affiliation-1 "Division of Periodontology, Department of Dentistry, All India Institute of Medical Sciences, Bathinda, India."), [Mehak Gupta](https://pubmed.ncbi.nlm.nih.gov/?term=Gupta+M&cauthor_id=42664116)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42664116/#short-view-affiliation-1 "Division of Periodontology, Department of Dentistry, All India Institute of Medical Sciences, Bathinda, India."), [Apurba Patra](https://pubmed.ncbi.nlm.nih.gov/?term=Patra+A&cauthor_id=42664116)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42664116/#short-view-affiliation-2 "Department of Anatomy, All India Institute of Medical Sciences, Bathinda."), [Anika Dawar](https://pubmed.ncbi.nlm.nih.gov/?term=Dawar+A&cauthor_id=42664116)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42664116/#short-view-affiliation-3 "Division of Periodontics, Centre of Dental Education and Research, All India Institute of Medical Sciences, Delhi, India.") ### Affiliations * 1 Division of Periodontology, Department of Dentistry, All India Institute of Medical Sciences, Bathinda, India. * 2 Department of Anatomy, All India Institute of Medical Sciences, Bathinda. * 3 Division of Periodontics, Centre of Dental Education and Research, All India Institute of Medical Sciences, Delhi, India. * PMID: **42664116** * DOI: [ 10.7417/CT.2026.2096 ](https://doi.org/10.7417/ct.2026.2096) Item in Clipboard Full text links Cite Display options Display options Format Abstract PubMed PMID ## Abstract **Background:** The present study aimed to determine the effectiveness of the microsurgical approach in treating gingival recession with collagen matrix by comparing it with Conventional surgery in terms of clinical and patient-centered outcomes. **Methods:** A total of 29 patients with bilateral gingival recession in the maxillary canine and/or premolar region were selected. After randomisation, bilateral recession sites were grouped into the test group (Microsurgery under 3.5 X magnification) and the control group (Conventional surgery). All the clinical and patient-reported parameters were recorded at baseline, 1, 3 and 6 months. **Results:** Both groups showed statistically significant differences in terms of reduction in gingival recession height (GRH), gingival recession width (GRW), clinical attachment level gain (CAL gain), increase in keratinized tissue thickness (KTT) and keratinized tissue width (KTW) after 6 months. But intergroup comparison showed no significant difference in terms of clinical parameters. The only significant difference was noted in terms of patient-centred parameters (Patient satisfactory score, Hypersensitivity score, Root aesthetic scores), which favoured the microsurgical group. **Conclusions:** Both groups demonstrated comparable clinical improvement; However, Patient-centred parameters were significantly better with the Microsurgical approach. Selection of the surgical approach should balance patient needs with practical considerations like cost, time, and clinician proficiency. **Keywords:** Dental; Dentin sensitivity; Gingival recession; Heterografts; Microsurgery; Patient reported outcome measures. [PubMed Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) ## Similar articles * [ Clinical efficacy of amniotic membrane and collagen membrane in conjunction with coronally advanced flap for the treatment of gingival recession: a randomized controlled trial. ](https://pubmed.ncbi.nlm.nih.gov/40899923/) Amaladhas MM, Pampani P, Shekar MK, Dharani K, Nallathambi K, Mani E.Amaladhas MM, et al.Quintessence Int. 2025 Dec 1;56(10):794-802. doi: 10.3290/j.qi.b6541904.Quintessence Int. 2025.PMID: 40899923Clinical Trial. * [ Treatment of multiple adjacent Miller class I and II gingival recessions with a Modified Coronally Advanced Tunnel (MCAT) technique and a collagen matrix or palatal connective tissue graft: a randomized, controlled clinical trial. ](https://pubmed.ncbi.nlm.nih.gov/23627374/) Aroca S, Molnár B, Windisch P, Gera I, Salvi GE, Nikolidakis D, Sculean A.Aroca S, et al.J Clin Periodontol. 2013 Jul;40(7):713-20. doi: 10.1111/jcpe.12112. Epub 2013 Apr 30.J Clin Periodontol. 2013.PMID: 23627374Clinical Trial. * [ A comparative study of the effects of advanced platelet-rich fibrin and resorbable collagen membrane in the treatment of gingival recession: a split-mouth, randomized clinical trial. ](https://pubmed.ncbi.nlm.nih.gov/39127674/) Al-Barakani MS, Al-Kadasi B, Al-Hajri M, Elayah SA.Al-Barakani MS, et al.Head Face Med. 2024 Aug 10;20(1):41. doi: 10.1186/s13005-024-00441-1.Head Face Med. 2024.PMID: 39127674Free PMC article.Clinical Trial. * [ Xenogeneic collagen matrix vs. connective tissue graft for the treatment of multiple gingival recession: a systematic review and meta-analysis. ](https://pubmed.ncbi.nlm.nih.gov/37898589/) Zegarra-Caceres L, Orellano-Merluzzi A, Muniz FWMG, de Souza SLS, Faveri M, Meza-Mauricio J.Zegarra-Caceres L, et al.Odontology. 2024 Apr;112(2):317-340. doi: 10.1007/s10266-023-00863-4. Epub 2023 Oct 29.Odontology. 2024.PMID: 37898589 * [ Periodontal soft tissue root coverage procedures: a systematic review from the AAP Regeneration Workshop. ](https://pubmed.ncbi.nlm.nih.gov/25644302/) Chambrone L, Tatakis DN.Chambrone L, et al.J Periodontol. 2015 Feb;86(2 Suppl):S8-51. doi: 10.1902/jop.2015.130674.J Periodontol. 2015.PMID: 25644302 [ See all similar articles ](https://pubmed.ncbi.nlm.nih.gov/?linkname=pubmed_pubmed&from_uid=42664116) ## Publication types * Randomized Controlled Trial Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Randomized+Controlled+Trial%22%5Bpt%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Randomized+Controlled+Trial) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Comparative Study Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Comparative+Study%22%5Bpt%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Comparative+Study) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Clinical Trial Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Clinical+Trial%22%5Bpt%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Clinical+Trial) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) ## MeSH terms * Adult Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Adult%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Adult) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Collagen* / therapeutic use Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Collagen%2Ftherapeutic+use%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Collagen) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Female Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Female%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Female) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Gingival Recession* / surgery Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Gingival+Recession%2Fsurgery%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Gingival+Recession) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Humans Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Humans) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Male Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Male%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Male) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Microsurgery* / methods Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Microsurgery%2Fmethods%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Microsurgery) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) * Treatment Outcome Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Treatment+Outcome%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Treatment+Outcome) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) ## Substances * Collagen Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Collagen%22%5Bnm%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=%22Collagen%22) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42664116/) ## LinkOut - 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