---
title: "Author correction: SCREESCO trial cumulative incidence estimates for colorectal cancer screening a"
id: "nature-3-author-correction-colonoscopy-and-fecal-immunochemical-testing-versus-usual"
canonical_url: "https://medichelpline.com/clinical-feed/nature-3-author-correction-colonoscopy-and-fecal-immunochemical-testing-versus-usual"
content_type: "clinical_feed_article"
specialty: "Gastroenterology"
source_name: "Nature Medicine"
source_url: "https://www.nature.com/articles/s41591-026-04702-1"
published_at: "2026-09-10T12:00:00.000Z"
evidence_level: "Journal Feed"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Author correction: SCREESCO trial cumulative incidence estimates for colorectal cancer screening a
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/nature-3-author-correction-colonoscopy-and-fecal-immunochemical-testing-versus-usual
- **Specialty:** [Gastroenterology](https://medichelpline.com/clinical-feed/gastroenterology.md)
- **Primary Source:** Nature Medicine
- **Source URL:** [Original Journal Publication](https://www.nature.com/articles/s41591-026-04702-1)
- **Published At:** 2026-09-10T12:00:00.000Z
- **Evidence Rating:** Journal Feed
## Executive GIST (TL;DR)
- This Author Correction concerns the SCREESCO randomized controlled trial comparing **colonoscopy** and **fecal immunochemical testing (FIT)** versus usual care for diagnostic colorectal cancer screening. - The correction updates the reported **cumulative incidence proportions** and their 95% confidence intervals (CIs) for colorectal cancer (CRC) at end of follow-up across four arms: primary colonoscopy arm, control arm, FIT×2 arm, and FIT×2 control arm. - Corrected cumulative incidence proportions and 95% CIs are: 0.69% (95% CI: 0.56–0.81%) for the primary **colonoscopy** arm; 0.72% (95% CI: 0.66–0.78%) for the control arm; 0.61% (95% CI: 0.54–0.68%) for the **FIT×2** arm; and 0.73% (95% CI: 0.67–0.79%) for the FIT×2 control arm. - The original article with the reported error was published online 20 February 2026 (DOI: 10.1038/s41591-026-04225-9); the Author Correction was published 10 September 2026 and the HTML and PDF have been updated. - The correction clarifies the numerical ranges only; no other corrections or changes to text, authorship, methods or outcomes are reported in this Correction notice. - The Correction and the underlying article are Open Access under a Creative Commons Attribution 4.0 International License. - Correspondence for the article is directed to Marcus Westerberg. Multiple authors and institutional affiliations across Sweden, the UK and other centres are listed in the Correction notice. - The Correction appears in Nature Medicine as an Author Correction and the version of record is dated 10 September 2026.
## Clinical Analysis & Structured Key Points
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[nature](https://www.nature.com/) 2. [nature medicine](https://www.nature.com/nm) 3. [author corrections](https://www.nature.com/nm/articles?type=author-correction) 4. article Author Correction: Colonoscopy and fecal immunochemical testing versus usual care in diagnostic colorectal cancer screening: the SCREESCO randomized controlled trial [ Download PDF ](https://www.nature.com/articles/s41591-026-04702-1.pdf) [ Download PDF ](https://www.nature.com/articles/s41591-026-04702-1.pdf) * Author Correction * [Open access](https://www.springernature.com/gp/open-science/about/the-fundamentals-of-open-access-and-open-research) * Published: 10 September 2026 # Author Correction: Colonoscopy and fecal immunochemical testing versus usual care in diagnostic colorectal cancer screening: the SCREESCO randomized controlled trial * [Marcus Westerberg](https://www.nature.com/articles/s41591-026-04702-1#auth-Marcus-Westerberg-Aff1) [ORCID: orcid.org/0000-0002-8906-6967](https://orcid.org/0000-0002-8906-6967)[1](https://www.nature.com/articles/s41591-026-04702-1#Aff1), * [Jonas F. Ludvigsson](https://www.nature.com/articles/s41591-026-04702-1#auth-Jonas_F_-Ludvigsson-Aff2-Aff3)[2](https://www.nature.com/articles/s41591-026-04702-1#Aff2),[3](https://www.nature.com/articles/s41591-026-04702-1#Aff3), * [Chris Metcalfe](https://www.nature.com/articles/s41591-026-04702-1#auth-Chris-Metcalfe-Aff4)[4](https://www.nature.com/articles/s41591-026-04702-1#Aff4), * [Ulf Strömberg](https://www.nature.com/articles/s41591-026-04702-1#auth-Ulf-Str_mberg-Aff5)[5](https://www.nature.com/articles/s41591-026-04702-1#Aff5), * [Johannes Blom](https://www.nature.com/articles/s41591-026-04702-1#auth-Johannes-Blom-Aff6-Aff7) [ORCID: orcid.org/0000-0002-4938-6640](https://orcid.org/0000-0002-4938-6640)[6](https://www.nature.com/articles/s41591-026-04702-1#Aff6),[7](https://www.nature.com/articles/s41591-026-04702-1#Aff7), * [Lars Engstrand](https://www.nature.com/articles/s41591-026-04702-1#auth-Lars-Engstrand-Aff8)[8](https://www.nature.com/articles/s41591-026-04702-1#Aff8), * [Mikael Hellström](https://www.nature.com/articles/s41591-026-04702-1#auth-Mikael-Hellstr_m-Aff9-Aff10) [ORCID: orcid.org/0000-0003-4031-332X](https://orcid.org/0000-0003-4031-332X)[9](https://www.nature.com/articles/s41591-026-04702-1#Aff9),[10](https://www.nature.com/articles/s41591-026-04702-1#Aff10), * [Christian Löwbeer](https://www.nature.com/articles/s41591-026-04702-1#auth-Christian-L_wbeer-Aff11-Aff12)[11](https://www.nature.com/articles/s41591-026-04702-1#Aff11),[12](https://www.nature.com/articles/s41591-026-04702-1#Aff12), * [Robert Steele](https://www.nature.com/articles/s41591-026-04702-1#auth-Robert-Steele-Aff13)[13](https://www.nature.com/articles/s41591-026-04702-1#Aff13), * [Lars Holmberg](https://www.nature.com/articles/s41591-026-04702-1#auth-Lars-Holmberg-Aff1-Aff14)[1](https://www.nature.com/articles/s41591-026-04702-1#Aff1),[14](https://www.nature.com/articles/s41591-026-04702-1#Aff14) & * … * [Anna Forsberg](https://www.nature.com/articles/s41591-026-04702-1#auth-Anna-Forsberg-Aff15) [ORCID: orcid.org/0000-0002-7048-3357](https://orcid.org/0000-0002-7048-3357)[15](https://www.nature.com/articles/s41591-026-04702-1#Aff15) Show authors [_Nature Medicine_](https://www.nature.com/nm) (2026) [Cite this article](https://www.nature.com/articles/s41591-026-04702-1#citeas) [ Save article ](https://www.nature.com/articles/s41591-026-04702-1/save-research?_csrf=ECNF8aDXphhvyG4WRhuKhkt7gtlDAkJP) [ View saved research ](https://www.nature.com/saved-research) The [Original Article](https://doi.org/10.1038/s41591-026-04225-9) was published on 20 February 2026 ### Explore related subjects Discover the latest articles and news in related subjects. * [Cancer screening](https://www.nature.com/subjects/cancer-screening) * [Colorectal cancer](https://www.nature.com/subjects/colorectal-cancer) Correction to: _Nature Medicine_ , published online 20 February 2026. In the version of the article initially published, in the first paragraph of the “Diagnostic yield of screening and usual care” section, the sentence “The corresponding cumulative incidence proportions at the end of follow-up of CRC were 0.69% (95% CI: 0.66–0.71%) in the primary colonoscopy arm, 0.72% (95% CI: 0.71–0.73%) in the control arm, 0.61% (95% CI: 0.60–0.63%) in the FIT×2 arm and 0.73% (95% CI: 0.72–0.75%) in the FIT×2 control arm” should have read “The corresponding cumulative incidence proportions at the end of follow-up of CRC were 0.69% (95% CI: 0.56-0.81%) in the primary colonoscopy arm, 0.72% (95% CI: 0.66-0.78%) in the control arm, 0.61% (95% CI: 0.54-0.68%) in the FIT×2 arm and 0.73% (95% CI: 0.67-0.79%) in the FIT×2 control arm”. This correction has been made in the HTML and PDF versions of the article. ## Author information ### Authors and Affiliations 1. Department of Surgical Sciences, Uppsala University, Uppsala, Sweden Marcus Westerberg & Lars Holmberg 2. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Jonas F. Ludvigsson 3. Department of Pediatrics, Örebro University Hospital, Örebro, Sweden Jonas F. Ludvigsson 4. Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK Chris Metcalfe 5. School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden Ulf Strömberg 6. Department of Surgery, Södersjukhuset, Stockholm, Sweden Johannes Blom 7. Department of Clinical Science and Education, Karolinska Institutet, Stockholm, Sweden Johannes Blom 8. Centre for Translational Microbiome Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden Lars Engstrand 9. Department of Radiology, Institute of Clinical Sciences at Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden Mikael Hellström 10. Department of Radiology, Sahlgrenska University Hospital, Gothenburg, Sweden Mikael Hellström 11. Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Stockholm, Sweden Christian Löwbeer 12. Department of Clinical Chemistry, SYNLAB Sverige, Täby, Sweden Christian Löwbeer 13. Department of Surgery, Population Health and Genomics, School of Medicine, University of Dundee, Ninewells Hospital, Dundee, UK Robert Steele 14. Translational Oncology & Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King’s College London, London, UK Lars Holmberg 15. Division of Clinical Epidemiology, Department of Medicine K2, Solna, Karolinska Institutet, Stockholm, Sweden Anna Forsberg Authors 1. 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