---
title: "Intravenous dexamethasone prolongs analgesia after supraclavicular brachial plexus block: randomiz"
id: "pubmed-42691058"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42691058"
content_type: "clinical_feed_article"
specialty: "General"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42691058/"
doi: "10.1371/journal.pone.0338067"
published_at: "2026-09-03T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Intravenous dexamethasone prolongs analgesia after supraclavicular brachial plexus block: randomiz
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42691058
- **Specialty:** [General](https://medichelpline.com/clinical-feed/general.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42691058/)
- **DOI:** [10.1371/journal.pone.0338067](https://doi.org/10.1371%2Fjournal.pone.0338067)
- **Published At:** 2026-09-03T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- This randomized clinical trial evaluated whether a single dose of **intravenous dexamethasone** prolongs postoperative analgesia after supraclavicular brachial plexus block (SCBPB) for upper limb surgery at Halibet National Referral Hospital, Eritrea. - Sixty adult patients undergoing upper limb surgery received SCBPB with 20 ml of 0.5% **bupivacaine** and were randomized to receive either 2 ml normal saline (control) or 2 ml (8 mg) intravenous dexamethasone (experimental). - Primary outcomes included pain scores, time to first rescue analgesia (duration of analgesia), and postoperative analgesic consumption; data were analyzed with SPSS v26. - The mean duration of analgesia was significantly longer with dexamethasone: 17.36 ± 3.75 hours versus 7.57 ± 1.04 hours in controls (p < 0.001). - The dexamethasone group experienced faster onset of both sensory and motor block and consumed less postoperative analgesic medication compared with controls. - No adverse events were reported in the trial, and the authors concluded intravenous dexamethasone is a practical adjunct to bupivacaine for SCBPB, particularly relevant in low-resource settings. - The trial was registered in the Pan African Clinical Trial Registry (PACTR202509579633417); recruitment ran from September 23, 2024, to January 17, 2025, with follow-up completed by January 18, 2025. - Conflict of interest: the authors declared no competing interests. Details such as randomization method, blinding procedures, exact pain score metrics, and full adverse-event monitoring protocols were not reported in the PubMed abstract.
## Clinical Analysis & Structured Key Points
Clipboard, Search History, and several other advanced features are temporarily unavailable. [ Skip to main page content ](https://pubmed.ncbi.nlm.nih.gov/42691058/#article-details) ![U.S. flag](https://cdn.ncbi.nlm.nih.gov/coreutils/uswds/img/favicons/favicon-57.png) An official website of the United States government Here's how you know ![Dot gov](https://cdn.ncbi.nlm.nih.gov/coreutils/uswds/img/icon-dot-gov.svg) **The .gov means it’s official.** Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. ![Https](https://cdn.ncbi.nlm.nih.gov/coreutils/uswds/img/icon-https.svg) **The site is secure.** The **https://** ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. [ ![NIH NLM Logo](https://cdn.ncbi.nlm.nih.gov/coreutils/nwds/img/logos/AgencyLogo.svg) ](https://www.ncbi.nlm.nih.gov/) [Log in](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42691058%2F) Show account info Close #### Account Logged in as: **username** * [Dashboard](https://www.ncbi.nlm.nih.gov/myncbi/) * [Publications](https://www.ncbi.nlm.nih.gov/myncbi/collections/bibliography/) * [Account settings](https://www.ncbi.nlm.nih.gov/account/settings/) * [Log out](https://www.ncbi.nlm.nih.gov/account/signout/?back_url=https%3A//pubmed.ncbi.nlm.nih.gov/42691058/) [Access keys](https://www.ncbi.nlm.nih.gov/guide/browsers/#ncbi_accesskeys) [NCBI Homepage](https://www.ncbi.nlm.nih.gov) [MyNCBI Homepage](https://pubmed.ncbi.nlm.nih.gov/myncbi/) [Main Content](https://pubmed.ncbi.nlm.nih.gov/42691058/#maincontent) [Main Navigation](https://pubmed.ncbi.nlm.nih.gov/42691058/) [ ![pubmed logo](https://cdn.ncbi.nlm.nih.gov/pubmed/c24ab723-7c80-48cd-9c68-022ded852586/core/images/pubmed-logo-blue.svg) ](https://pubmed.ncbi.nlm.nih.gov/) [ ](https://pubmed.ncbi.nlm.nih.gov/42691058/ "Show search bar") Search: [](https://pubmed.ncbi.nlm.nih.gov/42691058/ "Clear search input")Search [Advanced](https://pubmed.ncbi.nlm.nih.gov/advanced/) [ Clipboard ](https://pubmed.ncbi.nlm.nih.gov/clipboard/) [ User Guide ](https://pubmed.ncbi.nlm.nih.gov/help/) Save Email Send to * [ Clipboard ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * [My Bibliography](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42691058%2F%23open-bibliography-panel) * [Collections](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42691058%2F%23open-collections-panel) * [Citation manager](https://pubmed.ncbi.nlm.nih.gov/42691058/) Display options Display options Format Abstract PubMed PMID ## Save citation to file Format: Summary (text) PubMed PMID Abstract (text) CSV Create file Cancel ## Email citation Email address has not been verified. Go to [ My NCBI account settings ](https://account.ncbi.nlm.nih.gov/settings/) to confirm your email and then refresh this page. To: Subject: Body: Format: Summary Summary (text) Abstract Abstract (text) MeSH and other data Send email Cancel ### Add to Collections * Create a new collection * Add to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error [Please try again](https://pubmed.ncbi.nlm.nih.gov/42691058/) Add Cancel ### Add to My Bibliography * My Bibliography Unable to load your delegates due to an error [Please try again](https://pubmed.ncbi.nlm.nih.gov/42691058/) Add Cancel ## Your saved search Name of saved search: Search terms: [Test search terms](https://pubmed.ncbi.nlm.nih.gov/42691058/) Would you like email updates of new search results? Saved Search Alert Radio Buttons * Yes * No Email: ([change](https://www.ncbi.nlm.nih.gov/account/settings/)) Frequency: Monthly Weekly Daily Which day? The first Sunday The first Monday The first Tuesday The first Wednesday The first Thursday The first Friday The first Saturday The first day The first weekday Which day? Sunday Monday Tuesday Wednesday Thursday Friday Saturday Report format: Summary Summary (text) Abstract Abstract (text) PubMed Send at most: 1 item 5 items 10 items 20 items 50 items 100 items 200 items Send even when there aren't any new results Optional text in email: Save Cancel ## Create a file for external citation management software Create file Cancel ## Your RSS Feed Name of RSS Feed: Number of items displayed: 5 10 15 20 50 100 Create RSS Cancel RSS Link Copy ### Actions Cite Collections Add to Collections * Create a new collection * Add to an existing collection Name your collection: Name must be less than 100 characters Choose a collection: Unable to load your collection due to an error [Please try again](https://pubmed.ncbi.nlm.nih.gov/42691058/) Add Cancel Permalink Permalink Copy Display options Display options Format Abstract PubMed PMID ### Page navigation * [ Title & authors ](https://pubmed.ncbi.nlm.nih.gov/42691058/#heading) * [ Abstract ](https://pubmed.ncbi.nlm.nih.gov/42691058/#abstract) * [ Conflict of interest statement ](https://pubmed.ncbi.nlm.nih.gov/42691058/#conflict-of-interest) * [ Publication types ](https://pubmed.ncbi.nlm.nih.gov/42691058/#publication-types) * [ MeSH terms ](https://pubmed.ncbi.nlm.nih.gov/42691058/#mesh-terms) * [ Substances ](https://pubmed.ncbi.nlm.nih.gov/42691058/#substances) Title & authors Abstract Conflict of interest statement Publication types MeSH terms Substances Randomized Controlled Trial PLoS One Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22PLoS+One%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22PLoS+One%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) . 2026 Sep 3;21(9):e0338067. doi: 10.1371/journal.pone.0338067. eCollection 2026. # The effect of intravenous dexamethasone in supraclavicular brachial plexus block at Halibet National Referral Hospital, Eritrea 2024-2025: A randomized clinical trial [Michael Beraki Mengistu](https://pubmed.ncbi.nlm.nih.gov/?term=Mengistu+MB&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#full-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Senay Amare Habtu](https://pubmed.ncbi.nlm.nih.gov/?term=Habtu+SA&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#full-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Abel Mussie Elias](https://pubmed.ncbi.nlm.nih.gov/?term=Elias+AM&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#full-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Sabrina Hashim Idris](https://pubmed.ncbi.nlm.nih.gov/?term=Idris+SH&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#full-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Kisanet Huruy Abraha](https://pubmed.ncbi.nlm.nih.gov/?term=Abraha+KH&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#full-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea.") Affiliations Expand ### Affiliation * 1 Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea. * PMID: **42691058** * DOI: [ 10.1371/journal.pone.0338067 ](https://doi.org/10.1371/journal.pone.0338067) Item in Clipboard Randomized Controlled Trial # The effect of intravenous dexamethasone in supraclavicular brachial plexus block at Halibet National Referral Hospital, Eritrea 2024-2025: A randomized clinical trial Michael Beraki Mengistu et al. PLoS One. 2026. Show details Display options Display options Format Abstract PubMed PMID PLoS One Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22PLoS+One%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22PLoS+One%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) . 2026 Sep 3;21(9):e0338067. doi: 10.1371/journal.pone.0338067. eCollection 2026. ### Authors [Michael Beraki Mengistu](https://pubmed.ncbi.nlm.nih.gov/?term=Mengistu+MB&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#short-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Senay Amare Habtu](https://pubmed.ncbi.nlm.nih.gov/?term=Habtu+SA&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#short-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Abel Mussie Elias](https://pubmed.ncbi.nlm.nih.gov/?term=Elias+AM&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#short-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Sabrina Hashim Idris](https://pubmed.ncbi.nlm.nih.gov/?term=Idris+SH&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#short-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea."), [Kisanet Huruy Abraha](https://pubmed.ncbi.nlm.nih.gov/?term=Abraha+KH&cauthor_id=42691058)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691058/#short-view-affiliation-1 "Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea.") ### Affiliation * 1 Department of Nursing, Anesthesia Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea. * PMID: **42691058** * DOI: [ 10.1371/journal.pone.0338067 ](https://doi.org/10.1371/journal.pone.0338067) Item in Clipboard Cite Display options Display options Format Abstract PubMed PMID ## Abstract **Background:** Postoperative pain has significant impact on recovery and healthcare costs. While effective regional anesthesia provides both anesthesia and analgesia, its effects are often of limited duration. Previous studies indicate that intravenous dexamethasone may enhance and prolong analgesia when used with regional blocks, yet reports on its duration to supraclavicular brachial plexus block (SCBPB) for upper limb surgeries are limited. We hypothesized that intravenous dexamethasone would extend postoperative analgesia following SCBPB. **Method:** A randomized clinical trial was conducted at Halibet National Referral Hospital in Eritrea, involving 60 patients undergoing upper limb surgery who received SCBPB with 20 ml of 0.5% bupivacaine. Concurrently, the control group received 2 ml of normal saline, while the experimental group received 2 ml (8 mg) of intravenous dexamethasone. Pain scores, time to first rescue analgesia, and analgesic consumption were recorded. Data were analyzed using SPSS v26. **Results:** The mean duration of analgesia was significantly longer in the dexamethasone group (17.36 ± 3.75 hours) compared to the control group (7.57 ± 1.04 hours, p < 0.001). The dexamethasone group had faster onset of sensory and motor block and lower analgesic consumption. **Conclusions:** In summary, intravenous dexamethasone significantly prolonged postoperative analgesia, accelerated block onset, and reduced analgesic consumption without adverse events. These findings support its use as a practical adjunct to bupivacaine in supraclavicular brachial plexus block, with potential to improve postoperative pain management in low‑resource settings. **Clinical trial registration:** This trial was registered in the Pan African Clinical Trial Registry (PACTR202509579633417). Participant recruitment occurred between September 23, 2024 and January 17, 2025, with follow‑up completed by January 18, 2025. The authors confirm that all ongoing and related trials for this intervention are registered. Copyright: © 2026 Mengistu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. [PubMed Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) ## Conflict of interest statement The authors have declared that no competing interests exist. ## Publication types * Randomized Controlled Trial Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Randomized+Controlled+Trial%22%5Bpt%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Randomized+Controlled+Trial) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) ## MeSH terms * Administration, Intravenous Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Administration%2C+Intravenous%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Administration%2C+Intravenous) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Adult Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Adult%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Adult) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Anesthetics, Local / administration & dosage Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Anesthetics%2C+Local%2Fadministration+and+dosage%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Anesthetics%2C+Local) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Brachial Plexus Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Brachial+Plexus%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Brachial+Plexus) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Brachial Plexus Block* / methods Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Brachial+Plexus+Block%2Fmethods%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Brachial+Plexus+Block) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Bupivacaine / administration & dosage Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Bupivacaine%2Fadministration+and+dosage%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Bupivacaine) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Dexamethasone* / administration & dosage Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Dexamethasone%2Fadministration+and+dosage%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Dexamethasone) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Dexamethasone* / therapeutic use Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Dexamethasone%2Ftherapeutic+use%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Dexamethasone) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Female Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Female%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Female) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Humans Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Humans) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Male Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Male%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Male) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Middle Aged Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Middle+Aged%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Middle+Aged) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Postoperative Pain* / drug therapy Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Postoperative+Pain%2Fdrug+therapy%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Postoperative+Pain) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Postoperative Pain* / prevention & control Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Postoperative+Pain%2Fprevention+and+control%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Postoperative+Pain) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) ## Substances * Dexamethasone Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Dexamethasone%22%5Bnm%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=%22Dexamethasone%22) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Bupivacaine Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Bupivacaine%22%5Bnm%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=%22Bupivacaine%22) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) * Anesthetics, Local Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Anesthetics%2C+Local%22%5Bnm%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=%22Anesthetics%2C+Local%22) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691058/) [x] Cite Copy Download .nbib .nbib Format: AMA APA MLA NLM **Send To** * [Clipboard](https://pubmed.ncbi.nlm.nih.gov/42691058/) * [Email](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42691058%2F%23open-email-panel) * [Save](https://pubmed.ncbi.nlm.nih.gov/42691058/) * [My Bibliography](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42691058%2F%23open-bibliography-panel) * [Collections](https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F42691058%2F%23open-collections-panel) * [Citation Manager](https://pubmed.ncbi.nlm.nih.gov/42691058/) [x] NCBI Literature Resources [MeSH](https://www.ncbi.nlm.nih.gov/mesh/) [PMC](https://www.ncbi.nlm.nih.gov/pmc/) [Bookshelf](https://www.ncbi.nlm.nih.gov/books) [Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Unauthorized use of these marks is strictly prohibited. Follow NCBI [ Twitter ](https://twitter.com/ncbi) [ Facebook ](https://www.facebook.com/ncbi.nlm) [ LinkedIn ](https://www.linkedin.com/company/ncbinlm) [ GitHub ](https://github.com/ncbi) [ ](https://ncbiinsights.ncbi.nlm.nih.gov/) [Connect with NLM](https://www.nlm.nih.gov/socialmedia/index.html) * [ Twitter ](https://twitter.com/NLM_NIH) * [ SM-Facebook ](https://www.facebook.com/nationallibr
## Related Clinical Research

- [Single Preoperative Low-Dose Dexamethasone Lowers 1-Year Mortality After Geriatric Intertrochanter](https://medichelpline.com/clinical-feed/pubmed-40736223.md) (DOI: 10.1097/CM9.0000000000003731)
- [Liposomal Bupivacaine Plus Bupivacaine vs Bupivacaine ISB for Pain After Rotator Cuff Repair](https://medichelpline.com/clinical-feed/pubmed-41468585.md) (DOI: 10.5435/JAAOS-D-25-01002)
- [OCTA quantifies choroidal and retinal thinning and blood flow loss in lens-induced myopia rats](https://medichelpline.com/clinical-feed/plos-one-17-quantitative-analysis-of-choroidal-and-retinal-thickness-and-blood-flow-in-a.md)
- [Surgical-name Embeddings Using Large Language Models for Confounding Adjustment in Perioperative O](https://medichelpline.com/clinical-feed/medrxiv-14-large-language-model-embeddings-of-surgical-procedural-names-for-confounding.md)
- [FDA approves Zenbexus (iberdomide) for multiple myeloma, first of a novel drug class](https://medichelpline.com/clinical-feed/stat-news-1-stat-fda-approves-bristol-multiple-myeloma-treatment-marking-debut-of-novel.md)

## Navigation
- [← Back to General Feed](https://medichelpline.com/clinical-feed/general.md)
- [← All Clinical Specialties](https://medichelpline.com/clinical-feed.md)
## Medical & Regulatory Disclaimer

> [!CAUTION]
> MedicHelpline content is structured for research, educational, and professional discovery purposes. It does not constitute individual medical advice, clinical diagnosis, or treatment recommendations.
> Always verify dosing, contraindications, and regulatory alerts against official product labeling and primary regulatory sources before clinical decision-making.