---
title: "Telomere-to-telomere genome assembly for Botrytis cinerea strain B05.10"
id: "biorxiv-7-a-finished-telomere-to-telomere-assembly-for-botrytis-cinerea-strain-b05-10"
canonical_url: "https://medichelpline.com/clinical-feed/biorxiv-7-a-finished-telomere-to-telomere-assembly-for-botrytis-cinerea-strain-b05-10"
content_type: "clinical_feed_article"
specialty: "General"
source_name: "bioRxiv (Biomedical Preprints)"
source_url: "https://www.biorxiv.org/content/10.64898/2026.10.20.760327v1?rss=1"
published_at: "2026-10-25T12:00:00.000Z"
evidence_level: "Verified Feed"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Telomere-to-telomere genome assembly for Botrytis cinerea strain B05.10
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/biorxiv-7-a-finished-telomere-to-telomere-assembly-for-botrytis-cinerea-strain-b05-10
- **Specialty:** [General](https://medichelpline.com/clinical-feed/general.md)
- **Primary Source:** bioRxiv (Biomedical Preprints)
- **Source URL:** [Original Journal Publication](https://www.biorxiv.org/content/10.64898/2026.10.20.760327v1?rss=1)
- **Published At:** 2026-10-25T12:00:00.000Z
- **Evidence Rating:** Verified Feed
## Executive GIST (TL;DR)
- The authors produced an improved, finished **telomere-to-telomere** genome assembly for the fungal plant pathogen **Botrytis cinerea** strain **B05.10**. - The 2017 assembly was extended by adding eight telomeric regions; a small number of minor errors were corrected in the updated sequence. - The new assembly includes telomeres on every chromosome end except chromosome 4, which carries the ribosomal DNA (rDNA) repeat and therefore lacks telomeric sequence in this assembly. - The manuscript is a preprint and has not undergone peer review; authors reported deposition of the unannotated assembly in NCBI. - Manual curation of gene models is ongoing, according to the authors, and the finished assembly will be hosted on **Ensembl-Fungi** after structural curation is completed. - Data accession pointers provided in the preprint link the project to an NCBI BioProject and an SRA run accession (PRJNA15632; SRR40741277). - The study team declared no competing interests and listed funders 4TU-FairData and NWO. - Correspondence contact for the work is jan.vankan@wur.nl; authors are affiliated with Wageningen University, Laboratory of Phytopathology. - The preprint DOI is https://doi.org/10.64898/2026.10.20.760327 and the posting date is October 25, 2026.
## Clinical Analysis & Structured Key Points
A finished, telomere-to-telomere assembly for Botrytis cinerea strain B05.10 | bioRxiv Skip to main content New Results A finished, telomere-to-telomere assembly for Botrytis cinerea strain B05.10 View ORCID Profile Jan A.L. van Kan , View ORCID Profile Dian Zheng , View ORCID Profile Frank P.J. Pieterse , View ORCID Profile Xiaoqian Shi-Kunne doi: https://doi.org/10.64898/2026.10.20.760327 Jan A.L. van Kan Wageningen University, Laboratory of Phytopathology Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Jan A.L. van Kan For correspondence: jan.vankan{at}wur.nl Dian Zheng Wageningen University, Laboratory of Phytopathology Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Dian Zheng Frank P.J. Pieterse Wageningen University, Laboratory of Phytopathology Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Frank P.J. Pieterse Xiaoqian Shi-Kunne Wageningen University, Laboratory of Phytopathology Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Xiaoqian Shi-Kunne Abstract Info/History Metrics Data/Code Preview PDF Abstract We present an improved genome assembly of Botrytis cinerea strain B05.10 which serves as a reference isolate for most labs active in the Botrytis research. The existing assembly dating from 2017 was extended by adding 8 telomeric regions and a small number of minor errors was corrected. The new assembly contains telomeres on each chromosome end, except for Chr4 carrying the rDNA repeat. The unannotated assembly is deposited in NCBI and manual curation of gene models is ongoing. The new assembly will be hosted on Ensembl-Fungi after completion of the structural curation. Competing Interest Statement The authors have declared no competing interest. Footnotes https://www.ncbi.nlm.nih.gov/datasets/genome/?bioproject=PRJNA15632 https://www.ncbi.nlm.nih.gov/sra/?term=SRR40741277 Funder Information Declared 4TU-FairData NWO Copyright The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license . Back to top Previous Next Posted October 25, 2026. Download PDF Data/Code Email Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following A finished, telomere-to-telomere assembly for Botrytis cinerea strain B05.10 Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website. Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. Share A finished, telomere-to-telomere assembly for Botrytis cinerea strain B05.10 Jan A.L. van Kan , Dian Zheng , Frank P.J. Pieterse , Xiaoqian Shi-Kunne bioRxiv 2026.10.20.760327; doi: https://doi.org/10.64898/2026.10.20.760327 Share This Article: Copy Citation Tools A finished, telomere-to-telomere assembly for Botrytis cinerea strain B05.10 Jan A.L. van Kan , Dian Zheng , Frank P.J. Pieterse , Xiaoqian Shi-Kunne bioRxiv 2026.10.20.760327; doi: https://doi.org/10.64898/2026.10.20.760327 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Tweet Widget Facebook Like Google Plus One Subject Areas All Articles Animal Behavior and Cognition (8164) Biochemistry (19027) Bioengineering (15171) Bioinformatics (45372) Biophysics (22958) Cancer Biology (20120) Cell Biology (27314) Clinical Trials (138) Developmental Biology (14149) Ecology (21402) Epidemiology (2067) Evolutionary Biology (25816) Genetics (16349) Genomics (23848) Immunology (19033) Microbiology (43209) Molecular Biology (18346) Neuroscience (95152) Paleontology (714) Pathology (3036) Pharmacology and Toxicology (5201) Physiology (8287) Plant Biology (16274) Scientific Communication and Education (2116) Synthetic Biology (4647) Systems Biology (10389) Zoology (2427)
## Related Clinical Research

- [Correction Notice: Photovoice-Greenspaces Health Protocol Republished After Error](https://medichelpline.com/clinical-feed/plos-one-3-correction-a-scoping-review-of-photovoice-studies-concerning-greenspaces-and.md)
- [Stride-length alters energy flow through the upper extremity in baseball pitching](https://medichelpline.com/clinical-feed/plos-one-19-the-composition-of-energy-flow-in-the-upper-extremity-under-different-lower.md)
- [DELLA control of root transcriptional responses to water limitation in Arabidopsis and rice](https://medichelpline.com/clinical-feed/biorxiv-0-della-proteins-modulate-responsive-and-buffered-transcriptional-programs-in.md)
- [Causal analysis finds global rock-record influence on Phanerozoic marine biodiversity](https://medichelpline.com/clinical-feed/biorxiv-2-causal-analysis-of-rock-biodiversity-relationships-over-the-global-phanerozoic.md)
- [Rising caesarean use in Bangladesh 2012–2025: facility births and the private sector](https://medichelpline.com/clinical-feed/medrxiv-3-caesarean-section-in-bangladesh-2012-13-to-2025-facility-birth-the-private.md)

## Navigation
- [← Back to General Feed](https://medichelpline.com/clinical-feed/general.md)
- [← All Clinical Specialties](https://medichelpline.com/clinical-feed.md)
## Medical & Regulatory Disclaimer

> [!CAUTION]
> MedicHelpline content is structured for research, educational, and professional discovery purposes. It does not constitute individual medical advice, clinical diagnosis, or treatment recommendations.
> Always verify dosing, contraindications, and regulatory alerts against official product labeling and primary regulatory sources before clinical decision-making.