---
title: "Participant views on a person-centred Dynamic Choice model for mobile people in HIV care"
id: "pubmed-42691092"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42691092"
content_type: "clinical_feed_article"
specialty: "Infectious Disease"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42691092/"
doi: "10.1371/journal.pone.0356605"
published_at: "2026-09-03T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Participant views on a person-centred Dynamic Choice model for mobile people in HIV care
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42691092
- **Specialty:** [Infectious Disease](https://medichelpline.com/clinical-feed/infectious-disease.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42691092/)
- **DOI:** [10.1371/journal.pone.0356605](https://doi.org/10.1371%2Fjournal.pone.0356605)
- **Published At:** 2026-09-03T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- The study explored perceptions of a **person-centred dynamic choice** intervention designed for mobile people living with HIV in rural Kenya and Uganda. - Researchers conducted 23 qualitative interviews: 18 participants receiving care and 5 healthcare providers from eight communities in southwest Uganda and western Kenya. - The intervention offered multiple options: six-month and community ART refills, a **travel pack** (travel checklist, discreetly packed ART, emergency ART supply), phone access to a **mobility coordinator**, and facilitated transfers to distant clinics. - Participants valued having choices and flexibility; the **travel pack** was the most preferred component. - Longer intervals between clinic refills (six-month refills) reduced appointment burden and helped participants focus on **ART** adherence amid unpredictable mobility. - **Viral load counselling** was appreciated for clarifying links between adherence, viral load, and opportunistic infections. - Persistent structural barriers—poverty and food insecurity—were reported as ongoing obstacles to optimal adherence despite intervention benefits. - Participants recommended expanding support services to whole communities, adding care for other diseases, and providing food or employment support to improve outcomes. - Healthcare providers suggested strengthening supply chains and implementing electronic medical records nationally to better manage care for mobile patients. - The analysis used a framework approach on selected qualitative codes to identify emergent themes about intervention components and improvement recommendations.
## Clinical Analysis & Structured Key Points
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Participant perspectives on a person-centred care model for mobile individuals in HIV care from the SEARCH Dynamic Choice Treatment trial in rural Kenya and Uganda [Jason Johnson-Peretz](https://pubmed.ncbi.nlm.nih.gov/?term=Johnson-Peretz+J&cauthor_id=42691092)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-1 "Division of Prevention Sciences, University of California, San Francisco \(UCSF\), San Francisco, California, United States of America."), [James Ayieko](https://pubmed.ncbi.nlm.nih.gov/?term=Ayieko+J&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Lawrence Owino](https://pubmed.ncbi.nlm.nih.gov/?term=Owino+L&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Cecilia Akatukwasa](https://pubmed.ncbi.nlm.nih.gov/?term=Akatukwasa+C&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Anjeline Onyango](https://pubmed.ncbi.nlm.nih.gov/?term=Onyango+A&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Fred Atwine](https://pubmed.ncbi.nlm.nih.gov/?term=Atwine+F&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Titus O Arunga](https://pubmed.ncbi.nlm.nih.gov/?term=Arunga+TO&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Colette Aoko](https://pubmed.ncbi.nlm.nih.gov/?term=Aoko+C&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Laura B Balzer](https://pubmed.ncbi.nlm.nih.gov/?term=Balzer+LB&cauthor_id=42691092)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-4 "University of California, Berkeley, Biostatistics, Epidemiology, and Computational Precision Health, Berkeley, California, United States of America."), [Moses R Kamya](https://pubmed.ncbi.nlm.nih.gov/?term=Kamya+MR&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-5 "Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda."), [Edwin Charlesbois](https://pubmed.ncbi.nlm.nih.gov/?term=Charlesbois+E&cauthor_id=42691092)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-6 "University of California, San Francisco \(UCSF\), Medicine, San Francisco, California, United States of America."), [Jane Kabami](https://pubmed.ncbi.nlm.nih.gov/?term=Kabami+J&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Maya L Petersen](https://pubmed.ncbi.nlm.nih.gov/?term=Petersen+ML&cauthor_id=42691092)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-4 "University of California, Berkeley, Biostatistics, Epidemiology, and Computational Precision Health, Berkeley, California, United States of America."), [Gabriel Chamie](https://pubmed.ncbi.nlm.nih.gov/?term=Chamie+G&cauthor_id=42691092)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-6 "University of California, San Francisco \(UCSF\), Medicine, San Francisco, California, United States of America."), [Diane V Havlir](https://pubmed.ncbi.nlm.nih.gov/?term=Havlir+DV&cauthor_id=42691092)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-6 "University of California, San Francisco \(UCSF\), Medicine, San Francisco, California, United States of America."), [Elijah Kakande](https://pubmed.ncbi.nlm.nih.gov/?term=Kakande+E&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Carol S Camlin](https://pubmed.ncbi.nlm.nih.gov/?term=Camlin+CS&cauthor_id=42691092)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#full-view-affiliation-1 "Division of Prevention Sciences, University of California, San Francisco \(UCSF\), San Francisco, California, United States of America.") Affiliations Expand ### Affiliations * 1 Division of Prevention Sciences, University of California, San Francisco (UCSF), San Francisco, California, United States of America. * 2 Kenya Medical Research Institute (KEMRI), Kisumu, Kenya. * 3 Infectious Diseases Research Collaboration, Kampala, Uganda. * 4 University of California, Berkeley, Biostatistics, Epidemiology, and Computational Precision Health, Berkeley, California, United States of America. * 5 Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda. * 6 University of California, San Francisco (UCSF), Medicine, San Francisco, California, United States of America. * PMID: **42691092** * DOI: [ 10.1371/journal.pone.0356605 ](https://doi.org/10.1371/journal.pone.0356605) Item in Clipboard # Participant perspectives on a person-centred care model for mobile individuals in HIV care from the SEARCH Dynamic Choice Treatment trial in rural Kenya and Uganda Jason Johnson-Peretz et al. PLoS One. 2026. Show details Display options Display options Format Abstract PubMed PMID PLoS One Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22PLoS+One%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22PLoS+One%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42691092/) . 2026 Sep 3;21(9):e0356605. doi: 10.1371/journal.pone.0356605. eCollection 2026. ### Authors [Jason Johnson-Peretz](https://pubmed.ncbi.nlm.nih.gov/?term=Johnson-Peretz+J&cauthor_id=42691092)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-1 "Division of Prevention Sciences, University of California, San Francisco \(UCSF\), San Francisco, California, United States of America."), [James Ayieko](https://pubmed.ncbi.nlm.nih.gov/?term=Ayieko+J&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Lawrence Owino](https://pubmed.ncbi.nlm.nih.gov/?term=Owino+L&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Cecilia Akatukwasa](https://pubmed.ncbi.nlm.nih.gov/?term=Akatukwasa+C&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Anjeline Onyango](https://pubmed.ncbi.nlm.nih.gov/?term=Onyango+A&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Fred Atwine](https://pubmed.ncbi.nlm.nih.gov/?term=Atwine+F&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Titus O Arunga](https://pubmed.ncbi.nlm.nih.gov/?term=Arunga+TO&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Colette Aoko](https://pubmed.ncbi.nlm.nih.gov/?term=Aoko+C&cauthor_id=42691092)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-2 "Kenya Medical Research Institute \(KEMRI\), Kisumu, Kenya."), [Laura B Balzer](https://pubmed.ncbi.nlm.nih.gov/?term=Balzer+LB&cauthor_id=42691092)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-4 "University of California, Berkeley, Biostatistics, Epidemiology, and Computational Precision Health, Berkeley, California, United States of America."), [Moses R Kamya](https://pubmed.ncbi.nlm.nih.gov/?term=Kamya+MR&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-5 "Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda."), [Edwin Charlesbois](https://pubmed.ncbi.nlm.nih.gov/?term=Charlesbois+E&cauthor_id=42691092)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-6 "University of California, San Francisco \(UCSF\), Medicine, San Francisco, California, United States of America."), [Jane Kabami](https://pubmed.ncbi.nlm.nih.gov/?term=Kabami+J&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Maya L Petersen](https://pubmed.ncbi.nlm.nih.gov/?term=Petersen+ML&cauthor_id=42691092)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-4 "University of California, Berkeley, Biostatistics, Epidemiology, and Computational Precision Health, Berkeley, California, United States of America."), [Gabriel Chamie](https://pubmed.ncbi.nlm.nih.gov/?term=Chamie+G&cauthor_id=42691092)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-6 "University of California, San Francisco \(UCSF\), Medicine, San Francisco, California, United States of America."), [Diane V Havlir](https://pubmed.ncbi.nlm.nih.gov/?term=Havlir+DV&cauthor_id=42691092)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-6 "University of California, San Francisco \(UCSF\), Medicine, San Francisco, California, United States of America."), [Elijah Kakande](https://pubmed.ncbi.nlm.nih.gov/?term=Kakande+E&cauthor_id=42691092)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-3 "Infectious Diseases Research Collaboration, Kampala, Uganda."), [Carol S Camlin](https://pubmed.ncbi.nlm.nih.gov/?term=Camlin+CS&cauthor_id=42691092)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42691092/#short-view-affiliation-1 "Division of Prevention Sciences, University of California, San Francisco \(UCSF\), San Francisco, California, United States of America.") ### Affiliations * 1 Division of Prevention Sciences, University of California, San Francisco (UCSF), San Francisco, California, United States of America. * 2 Kenya Medical Research Institute (KEMRI), Kisumu, Kenya. * 3 Infectious Diseases Research Collaboration, Kampala, Uganda. * 4 University of California, Berkeley, Biostatistics, Epidemiology, and Computational Precision Health, Berkeley, California, United States of America. * 5 Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda. * 6 University of California, San Francisco (UCSF), Medicine, San Francisco, California, United States of America. * PMID: **42691092** * DOI: [ 10.1371/journal.pone.0356605 ](https://doi.org/10.1371/journal.pone.0356605) Item in Clipboard Cite Display options Display options Format Abstract PubMed PMID ## Abstract **Introduction:** Mobile populations experience difficulties maintaining antiretroviral therapy (ART) adherence and HIV care engagement. We sought to explore participant perceptions of a patient-centred model aimed at enhancing care engagement through 'dynamic choice' treatment services for mobile individuals. **Methods:** We conducted 23 qualitative interviews with participants (N = 18) and healthcare providers (N = 5) from eight communities in southwest Uganda and western Kenya enrolled in a dynamic choice intervention that provided six-month and community ART refills; a "travel pack" with a travel checklist, discreetly packed ART, and an emergency supply of ART; phone access to a mobility coordinator; and facilitated transfers to distal clinics. Interviews explored participant life and mobility contexts, intervention experiences and preferences (as recipient or provider), and patient-provider relations. We employed a framework analysis of selected codes to identify emergent themes around intervention components and recommendations for improvement. **Results:** Participants liked all options, the travel pack being most preferred. Longer times between refills allowed participants to concentrate on ART adherence, rather than on managing clinic appointments in the context of uncertain mobility. Viral load counselling was appreciated for explaining the relationship between medication adherence, viral load, and opportunistic infections. Poverty and food insecurity remain obstacles to ideal ART adherence. **Recommendations:** Participants suggested scaling up these support services to the whole community, incorporating services to treat additional diseases, and food or employment support to help improve overall health outcomes. Care providers also recommended strengthening supply chains and deploying electronic medical records country-wide to facilitate care for mobile individuals. Copyright: © 2026 Johnson-Peretz et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. [PubMed Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) ## Conflict of interest statement The authors have declared that no competing interests exist. ## MeSH terms * Adherence Interventions Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Adherence+Interventions%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Adherence+Interventions) * [ Add to Search ](https://pubme
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