---
title: "Anti-CD33 and polydopamine-coated curcumin‑ICG nanoparticles for in vitro leukemia cytotoxicity (s"
id: "pubmed-42508510"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42508510"
content_type: "clinical_feed_article"
specialty: "Oncology"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42508510/"
doi: "10.1016/j.ijpharm.2026.127202"
published_at: "2026-09-05T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Anti-CD33 and polydopamine-coated curcumin‑ICG nanoparticles for in vitro leukemia cytotoxicity (s
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42508510
- **Specialty:** [Oncology](https://medichelpline.com/clinical-feed/oncology.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42508510/)
- **DOI:** [10.1016/j.ijpharm.2026.127202](https://doi.org/10.1016%2Fj.ijpharm.2026.127202)
- **Published At:** 2026-09-05T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- The PubMed record (PMID: **42508510**) describes an article titled “Multifunctional anti-CD33 antibody- and polydopamine-coated curcumin-indocyanine green nanoparticles for in vitro cytotoxic effects against leukemia cells.” - The article is published in International Journal of Pharmaceutics (Int J Pharm) and is listed as a free article. - DOI is 10.1016/j.ijpharm.2026.127202; electronic publication date is 2026 Jul 27; journal citation shows 2026 Sep 5:702:127202. - The lead and coauthors include Pinyadapat Aroonthongsawat, Xue Feng, Yuxuan Ji, Yuxiang Xue, Nurbanu Ozgultekin, Hongdi Wang, Mengguang Ye, Norbert Radacsi, Primana Punnakitikashem, Xianfeng Chen, and Yaneenart Suwanwong; multiple institutional affiliations are provided. - Affiliations span Chulalongkorn University (Thailand), University of Edinburgh (United Kingdom), Siriraj Hospital/Mahidol University (Thailand) and related centers; corresponding author electronic addresses are given for Xianfeng Chen and Yaneenart Suwanwong in the PubMed entry. - The title indicates the study developed **multifunctional nanoparticles** featuring an **anti-CD33 antibody** and **polydopamine** coating with curcumin and indocyanine green (ICG) payloads, intended to assess **in vitro cytotoxic effects against leukemia cells**. - The PubMed page does not include the article abstract text or experimental details in the provided content; specific methods, results, quantitative outcomes, statistical analyses, and conclusions are not reported in the visible source content. - The record links to Elsevier Science full-text options; however, the PubMed entry itself contains only bibliographic and affiliation metadata and not the study’s data or conclusions. - Users seeking experimental details, cytotoxicity outcomes, or translational implications will need to consult the full text via the publisher link or institutional access because those details are not present on the PubMed summary page supplied here.
## Clinical Analysis & Structured Key Points
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Epub 2026 Jul 27. # Multifunctional anti-CD33 antibody- and polydopamine-coated curcumin-indocyanine green nanoparticles for in vitro cytotoxic effects against leukemia cells [Pinyadapat Aroonthongsawat](https://pubmed.ncbi.nlm.nih.gov/?term=Aroonthongsawat+P&cauthor_id=42508510)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-1 "Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Xue Feng](https://pubmed.ncbi.nlm.nih.gov/?term=Feng+X&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Yuxuan Ji](https://pubmed.ncbi.nlm.nih.gov/?term=Ji+Y&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Yuxiang Xue](https://pubmed.ncbi.nlm.nih.gov/?term=Xue+Y&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Nurbanu Ozgultekin](https://pubmed.ncbi.nlm.nih.gov/?term=Ozgultekin+N&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Hongdi Wang](https://pubmed.ncbi.nlm.nih.gov/?term=Wang+H&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Mengguang Ye](https://pubmed.ncbi.nlm.nih.gov/?term=Ye+M&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Norbert Radacsi](https://pubmed.ncbi.nlm.nih.gov/?term=Radacsi+N&cauthor_id=42508510)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-3 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland; School of Engineering, Institute for Materials and Processes, University of Edinburgh, Edinburgh EH9 3FB, The United Kingdom of Great Britain and Northern Ireland; Centre for Cardiovascular Science, The Queen's Medical Research Institute \(QMRI\), University of Edinburgh, BioQuarter, 47 Little France Crescent, Edinburgh EH16 4TJ, the United Kingdom of Great Britain and Northern Ireland."), [Primana Punnakitikashem](https://pubmed.ncbi.nlm.nih.gov/?term=Punnakitikashem+P&cauthor_id=42508510)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-4 "Department of Biochemistry, Faculty of Medicine, Siriraj Hospital, Bangkok 10700, Thailand; Siriraj Center of Research Excellence in Theranostic Nanomedicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand."), [Xianfeng Chen](https://pubmed.ncbi.nlm.nih.gov/?term=Chen+X&cauthor_id=42508510)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-5 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland; School of Engineering, Institute for Materials and Processes, University of Edinburgh, Edinburgh EH9 3FB, The United Kingdom of Great Britain and Northern Ireland. Electronic address: Michael.Chen@ed.ac.uk."), [Yaneenart Suwanwong](https://pubmed.ncbi.nlm.nih.gov/?term=Suwanwong+Y&cauthor_id=42508510)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#full-view-affiliation-6 "Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; Center of Excellence for Biosensors and Bioengineering \(CEBB\), Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: Yaneenart.s@chula.ac.th.") Affiliations Expand ### Affiliations * 1 Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland. * 2 School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland. * 3 School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland; School of Engineering, Institute for Materials and Processes, University of Edinburgh, Edinburgh EH9 3FB, The United Kingdom of Great Britain and Northern Ireland; Centre for Cardiovascular Science, The Queen's Medical Research Institute (QMRI), University of Edinburgh, BioQuarter, 47 Little France Crescent, Edinburgh EH16 4TJ, the United Kingdom of Great Britain and Northern Ireland. * 4 Department of Biochemistry, Faculty of Medicine, Siriraj Hospital, Bangkok 10700, Thailand; Siriraj Center of Research Excellence in Theranostic Nanomedicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand. * 5 School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland; School of Engineering, Institute for Materials and Processes, University of Edinburgh, Edinburgh EH9 3FB, The United Kingdom of Great Britain and Northern Ireland. Electronic address: Michael.Chen@ed.ac.uk. * 6 Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; Center of Excellence for Biosensors and Bioengineering (CEBB), Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: Yaneenart.s@chula.ac.th. * PMID: **42508510** * DOI: [ 10.1016/j.ijpharm.2026.127202 ](https://doi.org/10.1016/j.ijpharm.2026.127202) Free article Item in Clipboard # Multifunctional anti-CD33 antibody- and polydopamine-coated curcumin-indocyanine green nanoparticles for in vitro cytotoxic effects against leukemia cells Pinyadapat Aroonthongsawat et al. Int J Pharm. 2026. Free article Show details Display options Display options Format Abstract PubMed PMID Int J Pharm Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Int+J+Pharm%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Int+J+Pharm%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42508510/) . 2026 Sep 5:702:127202. doi: 10.1016/j.ijpharm.2026.127202. Epub 2026 Jul 27. ### Authors [Pinyadapat Aroonthongsawat](https://pubmed.ncbi.nlm.nih.gov/?term=Aroonthongsawat+P&cauthor_id=42508510)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-1 "Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Xue Feng](https://pubmed.ncbi.nlm.nih.gov/?term=Feng+X&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Yuxuan Ji](https://pubmed.ncbi.nlm.nih.gov/?term=Ji+Y&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Yuxiang Xue](https://pubmed.ncbi.nlm.nih.gov/?term=Xue+Y&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Nurbanu Ozgultekin](https://pubmed.ncbi.nlm.nih.gov/?term=Ozgultekin+N&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Hongdi Wang](https://pubmed.ncbi.nlm.nih.gov/?term=Wang+H&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Mengguang Ye](https://pubmed.ncbi.nlm.nih.gov/?term=Ye+M&cauthor_id=42508510)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-2 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland."), [Norbert Radacsi](https://pubmed.ncbi.nlm.nih.gov/?term=Radacsi+N&cauthor_id=42508510)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-3 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland; School of Engineering, Institute for Materials and Processes, University of Edinburgh, Edinburgh EH9 3FB, The United Kingdom of Great Britain and Northern Ireland; Centre for Cardiovascular Science, The Queen's Medical Research Institute \(QMRI\), University of Edinburgh, BioQuarter, 47 Little France Crescent, Edinburgh EH16 4TJ, the United Kingdom of Great Britain and Northern Ireland."), [Primana Punnakitikashem](https://pubmed.ncbi.nlm.nih.gov/?term=Punnakitikashem+P&cauthor_id=42508510)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-4 "Department of Biochemistry, Faculty of Medicine, Siriraj Hospital, Bangkok 10700, Thailand; Siriraj Center of Research Excellence in Theranostic Nanomedicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand."), [Xianfeng Chen](https://pubmed.ncbi.nlm.nih.gov/?term=Chen+X&cauthor_id=42508510)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-5 "School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland; School of Engineering, Institute for Materials and Processes, University of Edinburgh, Edinburgh EH9 3FB, The United Kingdom of Great Britain and Northern Ireland. Electronic address: Michael.Chen@ed.ac.uk."), [Yaneenart Suwanwong](https://pubmed.ncbi.nlm.nih.gov/?term=Suwanwong+Y&cauthor_id=42508510)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42508510/#short-view-affiliation-6 "Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; Center of Excellence for Biosensors and Bioengineering \(CEBB\), Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: Yaneenart.s@chula.ac.th.") ### Affiliations * 1 Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland. * 2 School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland. * 3 School of Engineering, Institute for Bioengineering, University of Edinburgh, The King's Buildings, Edinburgh EH9 3JL, The United Kingdom of Great Britain and Northern Ireland; School of Engineering, Institute for Materials and Processes, University of Edinburgh, Edinburgh EH9 3FB, The United Kingdom of Great Britain and Northern Ireland; Centre for Cardiovascular Science, The Queen's Medical Research Institute (QMRI), University of Edinburgh, BioQuarter, 47 Little France Crescent, Edinburgh EH16 4TJ, the United Kingdom of Great Britain and Northern Ireland. * 4 Department of Biochemistry
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