---
title: "Locally produced donor-derived anti-CD19 CAR T-cell outcomes in relapsed/refractory B-ALL"
id: "pubmed-42752932"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42752932"
content_type: "clinical_feed_article"
specialty: "Oncology"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42752932/"
doi: "10.1007/s00280-026-04952-3"
published_at: "2026-09-17T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Locally produced donor-derived anti-CD19 CAR T-cell outcomes in relapsed/refractory B-ALL
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42752932
- **Specialty:** [Oncology](https://medichelpline.com/clinical-feed/oncology.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42752932/)
- **DOI:** [10.1007/s00280-026-04952-3](https://doi.org/10.1007%2Fs00280-026-04952-3)
- **Published At:** 2026-09-17T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- PubMed entry for a 2026 Cancer Chemotherapy and Pharmacology article titled “Outcomes of locally produced donor-derived anti-CD19 chimeric antigen receptor T-cells in relapsed or refractory B-cell acute lymphoblastic leukemia patients.” - Article citation: Cancer Chemother Pharmacol. 2026 Sep 17;96(1):107. DOI 10.1007/s00280-026-04952-3. PMID 42752932. - Lead and coauthors listed (Supavich Tannumsaeng et al.) with multiple contributors affiliated primarily with Mahidol University departments and other Thai institutions. - Multiple institutional affiliations reported: Department of Pediatrics, Ramathibodi Hospital, Mahidol University; Ramathibodi Excellence Center for Cell and Gene Therapy; Siriraj Hospital; Department of Internal Medicine at Ramathibodi and Chiangmai University; Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University; Office of Health Sciences Research, Ramathibodi Hospital. - The PubMed record provides bibliographic metadata (title, journal, date, DOI, PMID, authors, affiliations) but the source content included here does not contain the article abstract, methods, results, patient numbers, safety data, efficacy outcomes, or specific conclusions. - Where details of study design, endpoints, outcomes, adverse events, manufacturing process, or statistical analysis would normally appear, the PubMed page text provided does not report them; those details must be obtained from the full-text article or complete PubMed abstract. - Contact emails for some corresponding authors are shown in the PubMed entry but no study data are reported in the clipped source text. - Readers interested in clinical data on **anti-CD19 CAR T-cells** in **B-cell acute lymphoblastic leukemia (B-ALL)** will need to access the full article via the DOI, publisher platform, or institutional resources because the supplied record lacks outcome information.
## Clinical Analysis & Structured Key Points
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](https://pubmed.ncbi.nlm.nih.gov/42752932/#abstract) * [ Conflict of interest statement ](https://pubmed.ncbi.nlm.nih.gov/42752932/#conflict-of-interest) * [ References ](https://pubmed.ncbi.nlm.nih.gov/42752932/#references) * [ MeSH terms ](https://pubmed.ncbi.nlm.nih.gov/42752932/#mesh-terms) * [ Substances ](https://pubmed.ncbi.nlm.nih.gov/42752932/#substances) Title & authors Abstract Conflict of interest statement References MeSH terms Substances Cancer Chemother Pharmacol Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Cancer+Chemother+Pharmacol%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Cancer+Chemother+Pharmacol%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42752932/) . 2026 Sep 17;96(1):107. doi: 10.1007/s00280-026-04952-3. # Outcomes of locally produced donor-derived anti-CD19 chimeric antigen receptor T-cells in relapsed or refractory B-cell acute lymphoblastic leukemia patients [Supavich Tannumsaeng](https://pubmed.ncbi.nlm.nih.gov/?term=Tannumsaeng+S&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Usanarat Anurathapan](https://pubmed.ncbi.nlm.nih.gov/?term=Anurathapan+U&cauthor_id=42752932)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-2 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. usanarat.anu@mahidol.ac.th.")[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-3 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. usanarat.anu@mahidol.ac.th."), [Arpatsorn Sermcheep](https://pubmed.ncbi.nlm.nih.gov/?term=Sermcheep+A&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Pattara Kanjanakan](https://pubmed.ncbi.nlm.nih.gov/?term=Kanjanakan+P&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Chayamon Takpradit](https://pubmed.ncbi.nlm.nih.gov/?term=Takpradit+C&cauthor_id=42752932)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-5 "Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Kleebsabai Sanpakit](https://pubmed.ncbi.nlm.nih.gov/?term=Sanpakit+K&cauthor_id=42752932)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-5 "Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Pimjai Niparuck](https://pubmed.ncbi.nlm.nih.gov/?term=Niparuck+P&cauthor_id=42752932)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-6 "Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Thanakrit Piyajaroenkij](https://pubmed.ncbi.nlm.nih.gov/?term=Piyajaroenkij+T&cauthor_id=42752932)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-6 "Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Adisak Tantiworawit](https://pubmed.ncbi.nlm.nih.gov/?term=Tantiworawit+A&cauthor_id=42752932)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-7 "Department of Internal Medicine, Faculty of Medicine, Chiangmai University, Chiangmai, Thailand."), [Korakot Atjanasuppat](https://pubmed.ncbi.nlm.nih.gov/?term=Atjanasuppat+K&cauthor_id=42752932)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Piamsiri Sawaisorn](https://pubmed.ncbi.nlm.nih.gov/?term=Sawaisorn+P&cauthor_id=42752932)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-8 "Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Nakhon Pathom, 73170, Thailand."), [Sarinthip Preedagasamzin](https://pubmed.ncbi.nlm.nih.gov/?term=Preedagasamzin+S&cauthor_id=42752932)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Bunyada Jittorntrum](https://pubmed.ncbi.nlm.nih.gov/?term=Jittorntrum+B&cauthor_id=42752932)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-9 "Office of Health Sciences Research, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Somsak Prasongtanakij](https://pubmed.ncbi.nlm.nih.gov/?term=Prasongtanakij+S&cauthor_id=42752932)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-9 "Office of Health Sciences Research, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Samart Pakakasama](https://pubmed.ncbi.nlm.nih.gov/?term=Pakakasama+S&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Suradej Hongeng](https://pubmed.ncbi.nlm.nih.gov/?term=Hongeng+S&cauthor_id=42752932)[ 10 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-10 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. suradej.hon@mahidol.ac.th.")[ 11 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#full-view-affiliation-11 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. suradej.hon@mahidol.ac.th.") Affiliations Expand ### Affiliations * 1 Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. * 2 Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. usanarat.anu@mahidol.ac.th. * 3 Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. usanarat.anu@mahidol.ac.th. * 4 Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. * 5 Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10400, Thailand. * 6 Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. * 7 Department of Internal Medicine, Faculty of Medicine, Chiangmai University, Chiangmai, Thailand. * 8 Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Nakhon Pathom, 73170, Thailand. * 9 Office of Health Sciences Research, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. * 10 Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. suradej.hon@mahidol.ac.th. * 11 Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. suradej.hon@mahidol.ac.th. * PMID: **42752932** * DOI: [ 10.1007/s00280-026-04952-3 ](https://doi.org/10.1007/s00280-026-04952-3) Item in Clipboard # Outcomes of locally produced donor-derived anti-CD19 chimeric antigen receptor T-cells in relapsed or refractory B-cell acute lymphoblastic leukemia patients Supavich Tannumsaeng et al. Cancer Chemother Pharmacol. 2026. Show details Display options Display options Format Abstract PubMed PMID Cancer Chemother Pharmacol Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Cancer+Chemother+Pharmacol%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Cancer+Chemother+Pharmacol%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42752932/) . 2026 Sep 17;96(1):107. doi: 10.1007/s00280-026-04952-3. ### Authors [Supavich Tannumsaeng](https://pubmed.ncbi.nlm.nih.gov/?term=Tannumsaeng+S&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Usanarat Anurathapan](https://pubmed.ncbi.nlm.nih.gov/?term=Anurathapan+U&cauthor_id=42752932)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-2 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. usanarat.anu@mahidol.ac.th.")[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-3 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. usanarat.anu@mahidol.ac.th."), [Arpatsorn Sermcheep](https://pubmed.ncbi.nlm.nih.gov/?term=Sermcheep+A&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Pattara Kanjanakan](https://pubmed.ncbi.nlm.nih.gov/?term=Kanjanakan+P&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Chayamon Takpradit](https://pubmed.ncbi.nlm.nih.gov/?term=Takpradit+C&cauthor_id=42752932)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-5 "Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Kleebsabai Sanpakit](https://pubmed.ncbi.nlm.nih.gov/?term=Sanpakit+K&cauthor_id=42752932)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-5 "Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Pimjai Niparuck](https://pubmed.ncbi.nlm.nih.gov/?term=Niparuck+P&cauthor_id=42752932)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-6 "Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Thanakrit Piyajaroenkij](https://pubmed.ncbi.nlm.nih.gov/?term=Piyajaroenkij+T&cauthor_id=42752932)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-6 "Department of Internal Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Adisak Tantiworawit](https://pubmed.ncbi.nlm.nih.gov/?term=Tantiworawit+A&cauthor_id=42752932)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-7 "Department of Internal Medicine, Faculty of Medicine, Chiangmai University, Chiangmai, Thailand."), [Korakot Atjanasuppat](https://pubmed.ncbi.nlm.nih.gov/?term=Atjanasuppat+K&cauthor_id=42752932)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Piamsiri Sawaisorn](https://pubmed.ncbi.nlm.nih.gov/?term=Sawaisorn+P&cauthor_id=42752932)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-8 "Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Nakhon Pathom, 73170, Thailand."), [Sarinthip Preedagasamzin](https://pubmed.ncbi.nlm.nih.gov/?term=Preedagasamzin+S&cauthor_id=42752932)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-4 "Department of Pediatrics and Ramathibodi Excellence Center for Cell and Gene Therapy, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Bunyada Jittorntrum](https://pubmed.ncbi.nlm.nih.gov/?term=Jittorntrum+B&cauthor_id=42752932)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-9 "Office of Health Sciences Research, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Somsak Prasongtanakij](https://pubmed.ncbi.nlm.nih.gov/?term=Prasongtanakij+S&cauthor_id=42752932)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-9 "Office of Health Sciences Research, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand."), [Samart Pakakasama](https://pubmed.ncbi.nlm.nih.gov/?term=Pakakasama+S&cauthor_id=42752932)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42752932/#short-view-affiliation-1 "Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/427
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