---
title: "Validation of Deauville Score 5a in Advanced-Stage Classic Hodgkin Lymphoma"
id: "pubmed-42379221"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42379221"
content_type: "clinical_feed_article"
specialty: "Oncology"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42379221/"
doi: "10.1182/bloodadvances.2026019712"
published_at: "2026-09-22T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Validation of Deauville Score 5a in Advanced-Stage Classic Hodgkin Lymphoma
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42379221
- **Specialty:** [Oncology](https://medichelpline.com/clinical-feed/oncology.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42379221/)
- **DOI:** [10.1182/bloodadvances.2026019712](https://doi.org/10.1182%2Fbloodadvances.2026019712)
- **Published At:** 2026-09-22T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- The article titled “Validation of the newly introduced Deauville score 5a for patients treated for advanced-stage classic Hodgkin lymphoma” was published in Blood Advances on 22 September 2026. - The study focuses on validating the newly introduced **Deauville score 5a** in patients with **advanced-stage classic Hodgkin lymphoma**, according to the title. - The work is a randomized controlled trial and lists multiple international coauthors from institutions in Germany, Switzerland, Austria, Australia, the Netherlands, Norway, Denmark, and Sweden. - The corresponding publication identifiers are PMID 42379221, PMCID PMC13578970, and DOI 10.1182/bloodadvances.2026019712. - Affiliations include the German Hodgkin Study Group, University Hospital Cologne, Swiss Cancer Institute Competence Center (Bern), Salzburg Cancer Research Institute, Inselspital Bern University Hospital, Prince of Wales Hospital (Sydney), Amsterdam University Medical Center, Oslo University Hospital, Nordic Lymphoma Group (Aarhus), and Uppsala University. - The PubMed entry links to a free full text at PubMed Central. - The PubMed page header and metadata are present in the source, but the provided source text did not include the article abstract, methods, results, statistical outcomes, or conclusions; these details were not reported in the supplied source content. - For complete study methods, validation metrics, and clinical implications of **Deauville score 5a**, readers should consult the full text available via the PMCID or the journal Blood Advances.
## Clinical Analysis & Structured Key Points
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newly introduced Deauville score 5a for patients treated for advanced-stage classic Hodgkin lymphoma [Simon Leiders](https://pubmed.ncbi.nlm.nih.gov/?term=Leiders+S&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany."), [Dominic Ufton](https://pubmed.ncbi.nlm.nih.gov/?term=Ufton+D&cauthor_id=42379221)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-3 "Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany."), [Helen Kaul](https://pubmed.ncbi.nlm.nih.gov/?term=Kaul+H&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany."), [Jasmin Weindler](https://pubmed.ncbi.nlm.nih.gov/?term=Weindler+J&cauthor_id=42379221)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-3 "Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany."), [Johannes Rosenbrock](https://pubmed.ncbi.nlm.nih.gov/?term=Rosenbrock+J&cauthor_id=42379221)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-4 "Department of Radiation Oncology and Cyberknife Center, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany."), [Michael Fuchs](https://pubmed.ncbi.nlm.nih.gov/?term=Fuchs+M&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany."), [Markus Dietlein](https://pubmed.ncbi.nlm.nih.gov/?term=Dietlein+M&cauthor_id=42379221)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-3 "Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany."), [Urban Novak](https://pubmed.ncbi.nlm.nih.gov/?term=Novak+U&cauthor_id=42379221)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-5 "Swiss Cancer Institute Competence Center, Bern, Switzerland.")[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-6 "Salzburg Cancer Research Institute-Center for Clinical Cancer and Immunology Trials and Arbeitsgemeinschaft Medikamentöse Tumortherapie, Salzburg, Austria."), [Martin Fehr](https://pubmed.ncbi.nlm.nih.gov/?term=Fehr+M&cauthor_id=42379221)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-5 "Swiss Cancer Institute Competence Center, Bern, Switzerland.")[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-7 "Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland."), [Richard Greil](https://pubmed.ncbi.nlm.nih.gov/?term=Greil+R&cauthor_id=42379221)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-6 "Salzburg Cancer Research Institute-Center for Clinical Cancer and Immunology Trials and Arbeitsgemeinschaft Medikamentöse Tumortherapie, Salzburg, Austria."), [Mark Hertzberg](https://pubmed.ncbi.nlm.nih.gov/?term=Hertzberg+M&cauthor_id=42379221)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-8 "Department of Haematology, Prince of Wales Hospital, and University of New South Wales, Sydney, NSW, Australia.")[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-9 "Australasian Leukaemia & Lymphoma Group, Melbourne, VIC, Australia."), [Josée M Zijlstra](https://pubmed.ncbi.nlm.nih.gov/?term=Zijlstra+JM&cauthor_id=42379221)[ 10 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-10 "Department of Hematology, Amsterdam University Medical Center, Vrije Universiteit, Cancer Center Amsterdam, Amsterdam, The Netherlands."), [Alexander Fosså](https://pubmed.ncbi.nlm.nih.gov/?term=Foss%C3%A5+A&cauthor_id=42379221)[ 11 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-11 "Department of Oncology, Oslo University Hospital, Oslo, Norway.")[ 12 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-12 "Nordic Lymphoma Group, Aarhus, Denmark."), [Peter Kamper](https://pubmed.ncbi.nlm.nih.gov/?term=Kamper+P&cauthor_id=42379221)[ 12 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-12 "Nordic Lymphoma Group, Aarhus, Denmark.")[ 13 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-13 "Department of Hematology, Aarhus University Hospital, Aarhus, Denmark."), [Daniel Molin](https://pubmed.ncbi.nlm.nih.gov/?term=Molin+D&cauthor_id=42379221)[ 12 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-12 "Nordic Lymphoma Group, Aarhus, Denmark.")[ 14 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-14 "Cancer Immunotherapy, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden."), [Peter Borchmann](https://pubmed.ncbi.nlm.nih.gov/?term=Borchmann+P&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany."), [Carsten Kobe](https://pubmed.ncbi.nlm.nih.gov/?term=Kobe+C&cauthor_id=42379221)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany.")[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-3 "Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany."), [Justin Ferdinandus](https://pubmed.ncbi.nlm.nih.gov/?term=Ferdinandus+J&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#full-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany.") Affiliations Expand ### Affiliations * 1 Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany. * 2 German Hodgkin Study Group, Cologne, Germany. * 3 Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany. * 4 Department of Radiation Oncology and Cyberknife Center, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany. * 5 Swiss Cancer Institute Competence Center, Bern, Switzerland. * 6 Salzburg Cancer Research Institute-Center for Clinical Cancer and Immunology Trials and Arbeitsgemeinschaft Medikamentöse Tumortherapie, Salzburg, Austria. * 7 Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland. * 8 Department of Haematology, Prince of Wales Hospital, and University of New South Wales, Sydney, NSW, Australia. * 9 Australasian Leukaemia & Lymphoma Group, Melbourne, VIC, Australia. * 10 Department of Hematology, Amsterdam University Medical Center, Vrije Universiteit, Cancer Center Amsterdam, Amsterdam, The Netherlands. * 11 Department of Oncology, Oslo University Hospital, Oslo, Norway. * 12 Nordic Lymphoma Group, Aarhus, Denmark. * 13 Department of Hematology, Aarhus University Hospital, Aarhus, Denmark. * 14 Cancer Immunotherapy, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. * PMID: **42379221** * PMCID: [ PMC13578970 ](https://pmc.ncbi.nlm.nih.gov/articles/PMC13578970/) * DOI: [ 10.1182/bloodadvances.2026019712 ](https://doi.org/10.1182/bloodadvances.2026019712) Item in Clipboard Randomized Controlled Trial # Validation of the newly introduced Deauville score 5a for patients treated for advanced-stage classic Hodgkin lymphoma Simon Leiders et al. Blood Adv. 2026. Show details Display options Display options Format Abstract PubMed PMID Blood Adv Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Blood+Adv%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Blood+Adv%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42379221/) . 2026 Sep 22;10(18):6112-6117. doi: 10.1182/bloodadvances.2026019712. ### Authors [Simon Leiders](https://pubmed.ncbi.nlm.nih.gov/?term=Leiders+S&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany."), [Dominic Ufton](https://pubmed.ncbi.nlm.nih.gov/?term=Ufton+D&cauthor_id=42379221)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-3 "Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany."), [Helen Kaul](https://pubmed.ncbi.nlm.nih.gov/?term=Kaul+H&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany."), [Jasmin Weindler](https://pubmed.ncbi.nlm.nih.gov/?term=Weindler+J&cauthor_id=42379221)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-3 "Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany."), [Johannes Rosenbrock](https://pubmed.ncbi.nlm.nih.gov/?term=Rosenbrock+J&cauthor_id=42379221)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany.")[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-4 "Department of Radiation Oncology and Cyberknife Center, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany."), [Michael Fuchs](https://pubmed.ncbi.nlm.nih.gov/?term=Fuchs+M&cauthor_id=42379221)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-1 "Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-2 "German Hodgkin Study Group, Cologne, Germany."), [Markus Dietlein](https://pubmed.ncbi.nlm.nih.gov/?term=Dietlein+M&cauthor_id=42379221)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-3 "Department of Nuclear Medicine, University Hospital Cologne, Cologne, Germany."), [Urban Novak](https://pubmed.ncbi.nlm.nih.gov/?term=Novak+U&cauthor_id=42379221)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-5 "Swiss Cancer Institute Competence Center, Bern, Switzerland.")[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-6 "Salzburg Cancer Research Institute-Center for Clinical Cancer and Immunology Trials and Arbeitsgemeinschaft Medikamentöse Tumortherapie, Salzburg, Austria."), [Martin Fehr](https://pubmed.ncbi.nlm.nih.gov/?term=Fehr+M&cauthor_id=42379221)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-5 "Swiss Cancer Institute Competence Center, Bern, Switzerland.")[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliation-7 "Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland."), [Richard Greil](https://pubmed.ncbi.nlm.nih.gov/?term=Greil+R&cauthor_id=42379221)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42379221/#short-view-affiliatio
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