---
title: "Contraceptive Use and Preferences in People with Cystic Fibrosis: Patterns and Influences"
id: "pubmed-42670820"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42670820"
content_type: "clinical_feed_article"
specialty: "Pediatrics"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42670820/"
doi: "10.1002/ppul.71809"
published_at: "2026-09-01T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Contraceptive Use and Preferences in People with Cystic Fibrosis: Patterns and Influences
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42670820
- **Specialty:** [Pediatrics](https://medichelpline.com/clinical-feed/pediatrics.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42670820/)
- **DOI:** [10.1002/ppul.71809](https://doi.org/10.1002%2Fppul.71809)
- **Published At:** 2026-09-01T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- Advancements in care for people with **cystic fibrosis** (PwCF) have increased the importance of reproductive health and contraception counseling. - A web-based survey was co-developed with Community Voice and distributed over five weeks (June–July 2025) to Community Voice and Elevate participants. - Eligibility: females with cystic fibrosis aged 18 years and older. - Ninety-seven PwCF completed the survey, representing 27 U.S. states and four Canadian provinces. - Among those currently using contraception, the most common methods were **intrauterine devices** (34%), **combined oral contraceptives** (28.3%), and condoms/barrier methods (24.5%). - Although 90% reported not actively trying to conceive, only 55% reported using any form of birth control. - Knowledge gaps were evident: misconceptions persisted about how common antibiotics affect contraceptive effectiveness. - Side effects were a dominant factor: 78.9% selected methods based on side-effect profiles (valued above efficacy), 68.6% reported experiencing side effects, and side effects were the leading reason for discontinuation. - Most respondents (68.1%) wanted contraception information from their CF care team, but only 28.9% reported receiving such education. - The authors conclude CF care teams, including pharmacists, can initiate and support contraception conversations and provide medication counseling to align choices with individual goals. - Keywords highlighted by the study include contraception, cystic fibrosis, pharmacy education, and sexual reproductive health.
## Clinical Analysis & Structured Key Points
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Affiliations Expand ### Affiliations * 1 UVA Health, Charlottesville, Virginia, USA. * 2 University of Utah Health, Salt Lake City, Utah, USA. * 3 Rush University Medical Center, Chicago, Illinois, USA. * 4 CHI St. Alexius Health, Bismarck, North Dakota, USA. * 5 University of California San Diego, La Jolla, California, USA. * PMID: **42670820** * DOI: [ 10.1002/ppul.71809 ](https://doi.org/10.1002/ppul.71809) Item in Clipboard # Reproductive Futures in Focus: Contraceptive Choices Among Individuals With Cystic Fibrosis-Patterns, Preferences, and Influencing Factors Kevin P Lonabaugh et al. Pediatr Pulmonol. 2026 Sep. Show details Display options Display options Format Abstract PubMed PMID Pediatr Pulmonol Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Pediatr+Pulmonol%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Pediatr+Pulmonol%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) . 2026 Sep;61(9):e71809. doi: 10.1002/ppul.71809. ### Authors [Kevin P Lonabaugh](https://pubmed.ncbi.nlm.nih.gov/?term=Lonabaugh+KP&cauthor_id=42670820)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42670820/#short-view-affiliation-1 "UVA Health, Charlottesville, Virginia, USA."), [HollyAnn Jacobs](https://pubmed.ncbi.nlm.nih.gov/?term=Jacobs+H&cauthor_id=42670820)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42670820/#short-view-affiliation-2 "University of Utah Health, Salt Lake City, Utah, USA."), [Jordan Orofino](https://pubmed.ncbi.nlm.nih.gov/?term=Orofino+J&cauthor_id=42670820)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42670820/#short-view-affiliation-3 "Rush University Medical Center, Chicago, Illinois, USA."), [Leanne Saville](https://pubmed.ncbi.nlm.nih.gov/?term=Saville+L&cauthor_id=42670820)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42670820/#short-view-affiliation-4 "CHI St. Alexius Health, Bismarck, North Dakota, USA."), [Brittany A Wright](https://pubmed.ncbi.nlm.nih.gov/?term=Wright+BA&cauthor_id=42670820)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42670820/#short-view-affiliation-5 "University of California San Diego, La Jolla, California, USA.") ### Affiliations * 1 UVA Health, Charlottesville, Virginia, USA. * 2 University of Utah Health, Salt Lake City, Utah, USA. * 3 Rush University Medical Center, Chicago, Illinois, USA. * 4 CHI St. Alexius Health, Bismarck, North Dakota, USA. * 5 University of California San Diego, La Jolla, California, USA. * PMID: **42670820** * DOI: [ 10.1002/ppul.71809 ](https://doi.org/10.1002/ppul.71809) Item in Clipboard Cite Display options Display options Format Abstract PubMed PMID ## Abstract **Introduction:** Advancements in the care of people with cystic fibrosis (PwCF) have made discussions about reproductive health increasingly important. Rising rates of both intended and unintended pregnancies highlight the need for effective contraception counseling. Understanding current contraception use patterns and identifying priorities for contraception education amongst PwCF are therefore essential. **Methods:** A web-based survey was developed in partnership with Community Voice, a virtual community of PwCF and their family members supported by the Cystic Fibrosis Foundation. The survey was distributed over a 5-week period (June-July 2025) to participants from Community Voice and Elevate. Females with cystic fibrosis aged 18 years and older were eligible to participate. **Results:** Ninety-seven PwCF completed the survey, representing 27 U.S. states and four Canadian provinces. Among individuals currently using contraception, the most common methods were intrauterine devices (34%), combined oral contraceptives (28.3%), and condoms/barrier methods (24.5%). Although 90% of PwCF were not actively trying to conceive, only 55% reported using a form of birth control. Knowledge-based questions revealed persistent misconceptions about the impact of common antibiotics on contraceptive effectiveness. While most PwCF (68.1%) wanted contraception information from their CF care team, only 28.9% reported receiving such education. Side effects were a major factor in decision-making: 78.9% selected contraceptive methods based on side-effect profiles (valued more than efficacy), 68.6% reported experiencing side effects, and side effects were the leading reason for contraception discontinuation. **Conclusion:** CF care teams can play a critical role in initiating and supporting conversations about contraception. Team members, including pharmacists, can provide medication counseling and help PwCF select contraceptive methods that align with their individual goals and needs. **Keywords:** contraception; cystic fibrosis; pharmacy education; sexual reproductive health. © 2026 The Author(s). Pediatric Pulmonology published by Wiley Periodicals LLC. [PubMed Disclaimer](https://pubmed.ncbi.nlm.nih.gov/disclaimer/) ## Similar articles * [ Contraceptive use and pregnancy in cystic fibrosis: Survey findings from 10 cystic fibrosis centers. ](https://pubmed.ncbi.nlm.nih.gov/39848844/) Godfrey EM, Magaret A, Roe A, Taylor-Cousar JL, Walker P, Langfelder-Schwind E, Kazmerski TM, Jain R, Mody SK, Uluer A, West NE, Bray LA, Hsu C, Fiastro A, Stukovsky KDH, Hadjiliadis D, Solomon GM, Ladores-Barrett S.Godfrey EM, et al.J Cyst Fibros. 2025 May;24(3):491-497. doi: 10.1016/j.jcf.2025.01.007. Epub 2025 Jan 22.J Cyst Fibros. 2025.PMID: 39848844Free PMC article. * [ Perspectives of people with cystic fibrosis considering parenthood surrounding preconception and prenatal genetic counseling and testing. ](https://pubmed.ncbi.nlm.nih.gov/40434014/) Rajanikanth G, Prangley A, Stransky OM, Langfelder-Schwind E, Vento J, Felter E, Kazmerski TM.Rajanikanth G, et al.Ther Adv Respir Dis. 2025 Jan-Dec;19:17534666251340334. doi: 10.1177/17534666251340334. Epub 2025 May 28.Ther Adv Respir Dis. 2025.PMID: 40434014Free PMC article. * [ Canadian Contraception Consensus (Part 1 of 4). ](https://pubmed.ncbi.nlm.nih.gov/26606712/) Black A, Guilbert E; Co-Authors; Costescu D, Dunn S, Fisher W, Kives S, Mirosh M, Norman WV, Pymar H, Reid R, Roy G, Varto H, Waddington A, Wagner MS, Whelan AM; Special Contributors; Ferguson C, Fortin C, Kielly M, Mansouri S, Todd N; Society of Obstetricians and Gynaecologists of Canada.Black A, et al.J Obstet Gynaecol Can. 2015 Oct;37(10):936-42. doi: 10.1016/s1701-2163(16)30033-0.J Obstet Gynaecol Can. 2015.PMID: 26606712English, French. * [ Canadian Contraception Consensus (Part 2 of 4). ](https://pubmed.ncbi.nlm.nih.gov/26629725/) Black A, Guilbert E; Co-Authors; Costescu D, Dunn S, Fisher W, Kives S, Mirosh M, Norman WV, Pymar H, Reid R, Roy G, Varto H, Waddington A, Wagner MS, Whelan AM; Special Contributors; Ferguson C, Fortin C, Kielly M, Mansouri S, Todd N.Black A, et al.J Obstet Gynaecol Can. 2015 Nov;37(11):1033-9. doi: 10.1016/s1701-2163(16)30054-8.J Obstet Gynaecol Can. 2015.PMID: 26629725English, French. * [ Personality Theories. ](https://pubmed.ncbi.nlm.nih.gov/42475469/) Gallios JM, Iyer V, Kaylor LE.Gallios JM, et al.2026 Jun 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–.2026 Jun 20. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–.PMID: 42475469Free Books & Documents. [ See all similar articles ](https://pubmed.ncbi.nlm.nih.gov/?linkname=pubmed_pubmed&from_uid=42670820) ## References 1. 1. A. Lopez, C. Daly, G. Vega‐Hernandez, G. MacGregor, and J. L. Rubin, “Elexacaftor/Tezacaftor/Ivacaftor Projected Survival and Long‐Term Health Outcomes in People With Cystic Fibrosis Homozygous for F508del,” Journal of Cystic Fibrosis 22, no. 4 (2023): 607–614, . 2. 1. C F FoundationCystic Fibrosis Foundation Patient Registry 2024 Annual Data Report. Cystic Fibrosis Foundation, 2025. 3. 1. C. A. Hodges, M. R. Palmert, and M. L. Drumm, “Infertility in Females With Cystic Fibrosis Is Multifactorial: Evidence From Mouse Models,” Endocrinology 149, no. 6 (2008): 2790–2797, . 4. 1. V. Sueblinvong and L. A. Whittaker, “Fertility and Pregnancy: Common Concerns of the Aging Cystic Fibrosis Population,” Clinics in Chest Medicine 28, no. 2 (2007): 433–443, . 5. 1. A. H. Roe, S. A. Traxler, D. Hadjiliadis, M. D. Sammel, and C. A. Schreiber, “Contraceptive Choices and Preferences in a Cohort of Women With Cystic Fibrosis,” Respiratory Medicine 121 (2016): 1–3, . Show all 29 references ## MeSH terms * Adolescent Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Adolescent%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Adolescent) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Adult Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Adult%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Adult) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Canada Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Canada%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Canada) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Contraception Behavior* / statistics & numerical data Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Contraception+Behavior%2Fstatistics+and+numerical+data%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Contraception+Behavior) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Contraception* / methods Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Contraception%2Fmethods%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Contraception) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Contraception* / statistics & numerical data Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Contraception%2Fstatistics+and+numerical+data%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Contraception) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Cystic Fibrosis* / psychology Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Cystic+Fibrosis%2Fpsychology%22%5BMAJR%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Cystic+Fibrosis) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Female Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Female%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Female) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Health Knowledge, Attitudes, Practice Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Health+Knowledge%2C+Attitudes%2C+Practice%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Health+Knowledge%2C+Attitudes%2C+Practice) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Humans Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Humans) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Pregnancy Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Pregnancy%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Pregnancy) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Surveys and Questionnaires Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Surveys+and+Questionnaires%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=Surveys+and+Questionnaires) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * United States Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22United+States%22%5BMeSH%5D&sort=date&sort_order=desc) * [ Search in MeSH ](https://www.ncbi.nlm.nih.gov/mesh?term=United+States) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42670820/) * Young Adult Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Young+Adult%22%5BMeSH%5D&sort=date&sort
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