---
title: "Cost-effectiveness of virtual pain coping skills training (mPCST) for women with breast cancer in"
id: "pubmed-42713766"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42713766"
content_type: "clinical_feed_article"
specialty: "Pharmacology"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42713766/"
doi: "10.1017/S1478951526103393"
published_at: "2026-09-09T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Cost-effectiveness of virtual pain coping skills training (mPCST) for women with breast cancer in
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42713766
- **Specialty:** [Pharmacology](https://medichelpline.com/clinical-feed/pharmacology.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42713766/)
- **DOI:** [10.1017/S1478951526103393](https://doi.org/10.1017%2FS1478951526103393)
- **Published At:** 2026-09-09T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- A randomized trial evaluated a 4-session virtually delivered pain coping skills training program (**mPCST**) for women with cancer living in medically underserved areas and found improved pain outcomes compared with an attention-control condition. - The study collected data on medical resource use, therapist time, participant attendance, travel time, and mobile app use; health-related quality of life (HRQOL) was measured with the **EQ-5D-5L** at baseline, post-intervention, and 3 and 6 months. - Medicare payments were used to value medical resource use and therapist time; patient time was valued using the average US wage. - Medical resource utilization was similar between groups, though hospitalizations trended higher in the mPCST group. - Across follow-up, EQ-5D-5L preference weights were higher by 0.066 (p = 0.04) with mPCST, yielding an incremental gain of 0.04 **quality-adjusted life years (QALYs)** (95% CI: 0.00–0.08). - Base-case incremental cost used a program cost of $500 for mPCST versus $0 for control, producing an incremental cost-effectiveness ratio (**ICER**) of $12,725 per QALY (95% CI: 5,566–69,343). - Including the value of patient time (adding $303 to mPCST costs) produced an ICER of $20,438 per QALY (95% CI: 9,051–111,403). - The authors conclude that mPCST is a **cost-effective** program that improves HRQOL for women with cancer in medically underserved areas. - Specific details about sample size, demographic breakdown, exact hospitalization counts, and longer-term costs beyond 6 months were not reported in the abstract and therefore are not available from the source provided.
## Clinical Analysis & Structured Key Points
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Affiliations Expand ### Affiliations * 1 Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA. * 2 Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA. * 3 Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA. * PMID: **42713766** * DOI: [ 10.1017/S1478951526103393 ](https://doi.org/10.1017/s1478951526103393) Item in Clipboard Randomized Controlled Trial # Cost-effectiveness analysis of a virtually administered pain coping skills training intervention in women with breast cancer in underserved areas Yanhong Li et al. Palliat Support Care. 2026. Show details Display options Display options Format Abstract PubMed PMID Palliat Support Care Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Palliat+Support+Care%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Palliat+Support+Care%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42713766/) . 2026 Sep 9:24:e216. doi: 10.1017/S1478951526103393. ### Authors [Yanhong Li](https://pubmed.ncbi.nlm.nih.gov/?term=Li+Y&cauthor_id=42713766)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-1 "Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA."), [Shelby D Reed](https://pubmed.ncbi.nlm.nih.gov/?term=Reed+SD&cauthor_id=42713766)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-1 "Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-2 "Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA."), [Joseph Giles Winger](https://pubmed.ncbi.nlm.nih.gov/?term=Winger+JG&cauthor_id=42713766)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-3 "Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA."), [Sarah Kelleher](https://pubmed.ncbi.nlm.nih.gov/?term=Kelleher+S&cauthor_id=42713766)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-2 "Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.")[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-3 "Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA."), [Hannah Fisher](https://pubmed.ncbi.nlm.nih.gov/?term=Fisher+H&cauthor_id=42713766)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-2 "Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.")[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-3 "Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA."), [Leah Zullig](https://pubmed.ncbi.nlm.nih.gov/?term=Zullig+L&cauthor_id=42713766)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-2 "Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA."), [Tamara J Somers](https://pubmed.ncbi.nlm.nih.gov/?term=Somers+TJ&cauthor_id=42713766)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42713766/#short-view-affiliation-3 "Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.") ### Affiliations * 1 Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA. * 2 Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA. * 3 Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA. * PMID: **42713766** * DOI: [ 10.1017/S1478951526103393 ](https://doi.org/10.1017/s1478951526103393) Item in Clipboard Cite Display options Display options Format Abstract PubMed PMID ## Abstract **Objectives:** Women with cancer who live in medically underserved areas could benefit from behavioral pain interventions, but access is limited. A randomized trial reported that a 4-session virtual program incorporating pain coping skills training (mPCST) was effective in improving pain outcomes compared to an attention-control condition. We performed a cost-effectiveness analysis of mPCST vs. control. **Methods:** Data on medical resource use, therapist time, and participants' attendance at intervention sessions and time associated with travel and using a mobile app were collected. The 5-level EuroQol 5-Dimension (EQ-5D-5L), a preference-weighted measure of health-related quality of life (HRQOL), was administered at baseline, after the intervention period, and 3 and 6 months later. Medicare payments were used to value medical resource use and therapist time to deliver mPCST. Patient time was valued using the average US wage. **Results:** Medical resource utilization was similar for both groups, but hospitalizations trended higher in the mPCST group. EQ-5D-5L preference weights were higher by an average of 0.066 (p = 0.04) with mPCST across the follow-up period, representing an incremental gain of 0.04 quality-adjusted life years (QALYs) (95% CI: 0.00-0.08). When including the base-case cost of mPCST of \$500 vs. \$0 for the control group, the incremental cost-effectiveness ratio (ICER) was \$12,725 per QALY (95% CI: 5,566-69,343). Including the value of patient time added \$303 to mPCST costs resulting in an ICER of \$20,438 per QALY (95% CI: 9,051-111,403). **Significance of results:** mPCST is a cost-effective program that improves HRQOL for women with cancer living in medically underserved areas. **Keywords:** Pain; behavioral interventions; cost-effectiveness analysis; economic evaluation; pain coping skills training. 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