---
title: "Management of Advanced Kidney Disease in Patients Over 80: Multicenter Spanish Observational Study"
id: "pubmed-42634179"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42634179"
content_type: "clinical_feed_article"
specialty: "Pharmacology"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42634179/"
doi: "10.1093/joneph/aajag108"
published_at: "2026-10-10T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Management of Advanced Kidney Disease in Patients Over 80: Multicenter Spanish Observational Study
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42634179
- **Specialty:** [Pharmacology](https://medichelpline.com/clinical-feed/pharmacology.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42634179/)
- **DOI:** [10.1093/joneph/aajag108](https://doi.org/10.1093%2Fjoneph%2Faajag108)
- **Published At:** 2026-10-10T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- This record describes a multicenter Spanish **observational study** published in J Nephrol assessing the impact of management of **advanced kidney disease** in **patients over 80**. - Citation metadata available: authorship led by Ignacio Gómez-Rojas et al., journal J Nephrol, publication date 2026 Oct 10, volume 39(6):1257-1265, PMID 42634179, DOI 10.1093/joneph/aajag108. - The study is affiliated with multiple Spanish nephrology departments and research institutes across Madrid and other Spanish provinces. - The PubMed entry classifies the work as an **Observational Study** and provides full author list and institutional affiliations. - The abstract text, methods, participant characteristics, specific interventions or management strategies, outcome measures, statistical results, and conclusions are not included in the PubMed page content provided. - Because the source body contains only bibliographic and administrative metadata, no study-specific findings, numerical outcomes, or clinical recommendations can be reported from this source alone. - Readers should consult the full-text article (DOI link provided) for details on study design, inclusion criteria, interventions compared, endpoints, results, and authors’ interpretations. - Key searchable identifiers present for follow-up: PMID 42634179 and DOI 10.1093/joneph/aajag108.
## Clinical Analysis & Structured Key Points
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types MeSH terms Related information Grants and funding LinkOut - more resources Observational Study J Nephrol Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22J+Nephrol%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22J+Nephrol%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42634179/) . 2026 Oct 10;39(6):1257-1265. doi: 10.1093/joneph/aajag108. # Impact of the management of advanced kidney disease in patients over 80 years of age: a multicenter Spanish study [Ignacio Gómez-Rojas](https://pubmed.ncbi.nlm.nih.gov/?term=G%C3%B3mez-Rojas+I&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-1 "Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain."), [Lucía Criado-Bellido](https://pubmed.ncbi.nlm.nih.gov/?term=Criado-Bellido+L&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain."), [José García-Casanova](https://pubmed.ncbi.nlm.nih.gov/?term=Garc%C3%ADa-Casanova+J&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain."), [Marina González de Rivera-Utrera](https://pubmed.ncbi.nlm.nih.gov/?term=Gonz%C3%A1lez+de+Rivera-Utrera+M&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain."), [Lucía Rodríguez-Gayo](https://pubmed.ncbi.nlm.nih.gov/?term=Rodr%C3%ADguez-Gayo+L&cauthor_id=42634179)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-3 "Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain."), [Irene Martín](https://pubmed.ncbi.nlm.nih.gov/?term=Mart%C3%ADn+I&cauthor_id=42634179)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-3 "Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain."), [Tatiana Niño](https://pubmed.ncbi.nlm.nih.gov/?term=Ni%C3%B1o+T&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-1 "Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain."), [Yanieli Hernández-Perdomo](https://pubmed.ncbi.nlm.nih.gov/?term=Hern%C3%A1ndez-Perdomo+Y&cauthor_id=42634179)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-4 "Nephrology Department, Hospital Universitario La Paz, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain."), [Lina M León-Machado](https://pubmed.ncbi.nlm.nih.gov/?term=Le%C3%B3n-Machado+LM&cauthor_id=42634179)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-4 "Nephrology Department, Hospital Universitario La Paz, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain."), [Diego Barbieri](https://pubmed.ncbi.nlm.nih.gov/?term=Barbieri+D&cauthor_id=42634179)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-6 "Nephrology Department, Hospital Clínico San Carlos, Madri, Spaind."), [Carlos Santos-Alonso](https://pubmed.ncbi.nlm.nih.gov/?term=Santos-Alonso+C&cauthor_id=42634179)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-7 "Nephrology Department, Hospital General de Segovia, Segovia, Spain."), [José C de la Flor](https://pubmed.ncbi.nlm.nih.gov/?term=de+la+Flor+JC&cauthor_id=42634179)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-8 "Nephrology Department, Hospital Central de La Defensa Gómez Ulla, Madrid, Spain."), [Laura Espinel](https://pubmed.ncbi.nlm.nih.gov/?term=Espinel+L&cauthor_id=42634179)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-9 "Nephrology Department, Hospital Universitario de Getafe, Madrid, Spain."), [Miguel A Navas](https://pubmed.ncbi.nlm.nih.gov/?term=Navas+MA&cauthor_id=42634179)[ 10 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-10 "Nephrology Department, Hospital Nuestra Señora de Sonsoles, Ávila, Spain."), [Adriana Puente-García](https://pubmed.ncbi.nlm.nih.gov/?term=Puente-Garc%C3%ADa+A&cauthor_id=42634179)[ 11 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-11 "Nephrology Department, Hospital Universitario de Fuenlabrada, Madrid, Spain."), [Miguel Villa-Valdés](https://pubmed.ncbi.nlm.nih.gov/?term=Villa-Vald%C3%A9s+M&cauthor_id=42634179)[ 12 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-12 "Nephrology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain."), [Alberto Ortiz](https://pubmed.ncbi.nlm.nih.gov/?term=Ortiz+A&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain."), [María A Bajo](https://pubmed.ncbi.nlm.nih.gov/?term=Bajo+MA&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-1 "Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain.")[ 13 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-13 "Instituto de Investigación Sanitaria La Princesa \(IIS-Princesa\), Madrid, Spain."), [Borja Quiroga](https://pubmed.ncbi.nlm.nih.gov/?term=Quiroga+B&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-1 "Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain.")[ 13 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#full-view-affiliation-13 "Instituto de Investigación Sanitaria La Princesa \(IIS-Princesa\), Madrid, Spain.") Affiliations Expand ### Affiliations * 1 Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain. * 2 Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain. * 3 Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain. * 4 Nephrology Department, Hospital Universitario La Paz, Madrid, Spain. * 5 RICORS 2040-Renal, Instituto de Salud Carlos III (ISCIII), Madrid, Spain. * 6 Nephrology Department, Hospital Clínico San Carlos, Madri, Spaind. * 7 Nephrology Department, Hospital General de Segovia, Segovia, Spain. * 8 Nephrology Department, Hospital Central de La Defensa Gómez Ulla, Madrid, Spain. * 9 Nephrology Department, Hospital Universitario de Getafe, Madrid, Spain. * 10 Nephrology Department, Hospital Nuestra Señora de Sonsoles, Ávila, Spain. * 11 Nephrology Department, Hospital Universitario de Fuenlabrada, Madrid, Spain. * 12 Nephrology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain. * 13 Instituto de Investigación Sanitaria La Princesa (IIS-Princesa), Madrid, Spain. * PMID: **42634179** * DOI: [ 10.1093/joneph/aajag108 ](https://doi.org/10.1093/joneph/aajag108) Item in Clipboard Observational Study # Impact of the management of advanced kidney disease in patients over 80 years of age: a multicenter Spanish study Ignacio Gómez-Rojas et al. J Nephrol. 2026. Show details Display options Display options Format Abstract PubMed PMID J Nephrol Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22J+Nephrol%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22J+Nephrol%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42634179/) . 2026 Oct 10;39(6):1257-1265. doi: 10.1093/joneph/aajag108. ### Authors [Ignacio Gómez-Rojas](https://pubmed.ncbi.nlm.nih.gov/?term=G%C3%B3mez-Rojas+I&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-1 "Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain."), [Lucía Criado-Bellido](https://pubmed.ncbi.nlm.nih.gov/?term=Criado-Bellido+L&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain."), [José García-Casanova](https://pubmed.ncbi.nlm.nih.gov/?term=Garc%C3%ADa-Casanova+J&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain."), [Marina González de Rivera-Utrera](https://pubmed.ncbi.nlm.nih.gov/?term=Gonz%C3%A1lez+de+Rivera-Utrera+M&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain."), [Lucía Rodríguez-Gayo](https://pubmed.ncbi.nlm.nih.gov/?term=Rodr%C3%ADguez-Gayo+L&cauthor_id=42634179)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-3 "Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain."), [Irene Martín](https://pubmed.ncbi.nlm.nih.gov/?term=Mart%C3%ADn+I&cauthor_id=42634179)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-3 "Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain."), [Tatiana Niño](https://pubmed.ncbi.nlm.nih.gov/?term=Ni%C3%B1o+T&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-1 "Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain."), [Yanieli Hernández-Perdomo](https://pubmed.ncbi.nlm.nih.gov/?term=Hern%C3%A1ndez-Perdomo+Y&cauthor_id=42634179)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-4 "Nephrology Department, Hospital Universitario La Paz, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain."), [Lina M León-Machado](https://pubmed.ncbi.nlm.nih.gov/?term=Le%C3%B3n-Machado+LM&cauthor_id=42634179)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-4 "Nephrology Department, Hospital Universitario La Paz, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain."), [Diego Barbieri](https://pubmed.ncbi.nlm.nih.gov/?term=Barbieri+D&cauthor_id=42634179)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-6 "Nephrology Department, Hospital Clínico San Carlos, Madri, Spaind."), [Carlos Santos-Alonso](https://pubmed.ncbi.nlm.nih.gov/?term=Santos-Alonso+C&cauthor_id=42634179)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-7 "Nephrology Department, Hospital General de Segovia, Segovia, Spain."), [José C de la Flor](https://pubmed.ncbi.nlm.nih.gov/?term=de+la+Flor+JC&cauthor_id=42634179)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-8 "Nephrology Department, Hospital Central de La Defensa Gómez Ulla, Madrid, Spain."), [Laura Espinel](https://pubmed.ncbi.nlm.nih.gov/?term=Espinel+L&cauthor_id=42634179)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-9 "Nephrology Department, Hospital Universitario de Getafe, Madrid, Spain."), [Miguel A Navas](https://pubmed.ncbi.nlm.nih.gov/?term=Navas+MA&cauthor_id=42634179)[ 10 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-10 "Nephrology Department, Hospital Nuestra Señora de Sonsoles, Ávila, Spain."), [Adriana Puente-García](https://pubmed.ncbi.nlm.nih.gov/?term=Puente-Garc%C3%ADa+A&cauthor_id=42634179)[ 11 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-11 "Nephrology Department, Hospital Universitario de Fuenlabrada, Madrid, Spain."), [Miguel Villa-Valdés](https://pubmed.ncbi.nlm.nih.gov/?term=Villa-Vald%C3%A9s+M&cauthor_id=42634179)[ 12 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-12 "Nephrology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain."), [Alberto Ortiz](https://pubmed.ncbi.nlm.nih.gov/?term=Ortiz+A&cauthor_id=42634179)[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-2 "Nephrology and Hypertension Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain."), [María A Bajo](https://pubmed.ncbi.nlm.nih.gov/?term=Bajo+MA&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-1 "Nephrology Department, Hospital Universitario de la Princesa, Madrid, Spain.")[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-5 "RICORS 2040-Renal, Instituto de Salud Carlos III \(ISCIII\), Madrid, Spain.")[ 13 ](https://pubmed.ncbi.nlm.nih.gov/42634179/#short-view-affiliation-13 "Instituto de Investigación Sanitaria La Princesa \(IIS-Princesa\), Madrid, Spain."), [Borja Quiroga](https://pubmed.ncbi.nlm.nih.gov/?term=Quiroga+B&cauthor_id=42634179)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42634179/
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