---
title: "Prognostic Survival Risk Score for Lung Cancer Patients with Type 2 Diabetes: Territory-Wide Retro"
id: "pubmed-42655935"
canonical_url: "https://medichelpline.com/clinical-feed/pubmed-42655935"
content_type: "clinical_feed_article"
specialty: "Pharmacology"
source_name: "PubMed / NCBI"
source_url: "https://pubmed.ncbi.nlm.nih.gov/42655935/"
doi: "10.1002/cam4.72164"
published_at: "2026-09-01T00:00:00.000Z"
evidence_level: "Journal Article"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Prognostic Survival Risk Score for Lung Cancer Patients with Type 2 Diabetes: Territory-Wide Retro
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/pubmed-42655935
- **Specialty:** [Pharmacology](https://medichelpline.com/clinical-feed/pharmacology.md)
- **Primary Source:** PubMed / NCBI
- **Source URL:** [Original Journal Publication](https://pubmed.ncbi.nlm.nih.gov/42655935/)
- **DOI:** [10.1002/cam4.72164](https://doi.org/10.1002%2Fcam4.72164)
- **Published At:** 2026-09-01T00:00:00.000Z
- **Evidence Rating:** Journal Article
## Executive GIST (TL;DR)
- This publication, titled “Development of a Prognostic Survival Risk Score for Lung Cancer Patients With Type 2 Diabetes Mellitus: A Territory-Wide Retrospective Cohort Study,” appears in Cancer Medicine (2026 Sep;15[9]:e72164) with DOI 10.1002/cam4.72164 and PubMed ID 42655935. - The study was performed by a multi‑institutional team led by Claire Chenwen Zhong and colleagues, with affiliations including The Chinese University of Hong Kong, Sun Yat‑sen University, Nankai University, Huazhong University of Science and Technology, Hospital Authority (Hong Kong), and Stanford University. - The article reports development of a **prognostic survival risk score** for patients who have both **lung cancer** and **type 2 diabetes mellitus (T2DM)**, using a **territory‑wide retrospective cohort** design. - The record includes a PMCID (PMC13519287), indicating a free full text is available via PubMed Central. - The PubMed entry links to a Wiley full‑text option and the free PMC article. - The PubMed record lists a broad author team with contributions from public health, oncology, radiation oncology, artificial intelligence/robotics, gastroenterology, health informatics, computer science, and pulmonary/critical care medicine. - The PubMed entry provides bibliographic metadata (journal, issue, DOI, PMID, PMCID, author list, and institutional affiliations) but the provided excerpt does not include the article abstract, specific methods, cohort size, predictor variables, statistical model details, performance metrics, or study outcomes. - Where specific study details (sample size, inclusion/exclusion criteria, predictors retained, model discrimination/calibration, validation approach, and clinical recommendations) are not reported in the visible PubMed record, those details are unavailable from this source and are noted as not reported.
## Clinical Analysis & Structured Key Points
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References MeSH terms LinkOut - more resources Cancer Med Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Cancer+Med%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Cancer+Med%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42655935/) . 2026 Sep;15(9):e72164. doi: 10.1002/cam4.72164. # Development of a Prognostic Survival Risk Score for Lung Cancer Patients With Type 2 Diabetes Mellitus: A Territory-Wide Retrospective Cohort Study [Claire Chenwen Zhong](https://pubmed.ncbi.nlm.nih.gov/?term=Zhong+CC&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Junjie Huang](https://pubmed.ncbi.nlm.nih.gov/?term=Huang+J&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Zhaojun Li](https://pubmed.ncbi.nlm.nih.gov/?term=Li+Z&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Yu Jiang](https://pubmed.ncbi.nlm.nih.gov/?term=Jiang+Y&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Zehuan Yang](https://pubmed.ncbi.nlm.nih.gov/?term=Yang+Z&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Jinqiu Yuan](https://pubmed.ncbi.nlm.nih.gov/?term=Yuan+J&cauthor_id=42655935)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-3 "Clinical Research Center & Big Data Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China."), [Xiaodan Huang](https://pubmed.ncbi.nlm.nih.gov/?term=Huang+X&cauthor_id=42655935)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-4 "State Key Laboratory of Oncology in South China, Department of Radiation Oncology, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China."), [Xiaofang Liu](https://pubmed.ncbi.nlm.nih.gov/?term=Liu+X&cauthor_id=42655935)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-5 "Institute of Robotics and Automatic Information Systems, College of Artificial Intelligence, Nankai University, Tianjin, China."), [Han Wang](https://pubmed.ncbi.nlm.nih.gov/?term=Wang+H&cauthor_id=42655935)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-6 "Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China."), [Jonathan Poon](https://pubmed.ncbi.nlm.nih.gov/?term=Poon+J&cauthor_id=42655935)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-7 "Information Technology and Health Informatics Division, Hospital Authority, Hong Kong SAR, China."), [Qi Dou](https://pubmed.ncbi.nlm.nih.gov/?term=Dou+Q&cauthor_id=42655935)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-8 "Department of Computer Science and Engineering, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Arthur Sung](https://pubmed.ncbi.nlm.nih.gov/?term=Sung+A&cauthor_id=42655935)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-9 "Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA."), [Martin C S Wong](https://pubmed.ncbi.nlm.nih.gov/?term=Wong+MCS&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#full-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.") Affiliations Expand ### Affiliations * 1 The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. * 2 Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. * 3 Clinical Research Center & Big Data Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China. * 4 State Key Laboratory of Oncology in South China, Department of Radiation Oncology, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China. * 5 Institute of Robotics and Automatic Information Systems, College of Artificial Intelligence, Nankai University, Tianjin, China. * 6 Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. * 7 Information Technology and Health Informatics Division, Hospital Authority, Hong Kong SAR, China. * 8 Department of Computer Science and Engineering, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. * 9 Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA. * PMID: **42655935** * PMCID: [ PMC13519287 ](https://pmc.ncbi.nlm.nih.gov/articles/PMC13519287/) * DOI: [ 10.1002/cam4.72164 ](https://doi.org/10.1002/cam4.72164) Item in Clipboard # Development of a Prognostic Survival Risk Score for Lung Cancer Patients With Type 2 Diabetes Mellitus: A Territory-Wide Retrospective Cohort Study Claire Chenwen Zhong et al. Cancer Med. 2026 Sep. Show details Display options Display options Format Abstract PubMed PMID Cancer Med Actions * [ Search in PubMed ](https://pubmed.ncbi.nlm.nih.gov/?term=%22Cancer+Med%22%5Bjour%5D&sort=date&sort_order=desc) * [ Search in NLM Catalog ](https://www.ncbi.nlm.nih.gov/nlmcatalog?term=%22Cancer+Med%22%5BTitle+Abbreviation%5D) * [ Add to Search ](https://pubmed.ncbi.nlm.nih.gov/42655935/) . 2026 Sep;15(9):e72164. doi: 10.1002/cam4.72164. ### Authors [Claire Chenwen Zhong](https://pubmed.ncbi.nlm.nih.gov/?term=Zhong+CC&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Junjie Huang](https://pubmed.ncbi.nlm.nih.gov/?term=Huang+J&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Zhaojun Li](https://pubmed.ncbi.nlm.nih.gov/?term=Li+Z&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Yu Jiang](https://pubmed.ncbi.nlm.nih.gov/?term=Jiang+Y&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Zehuan Yang](https://pubmed.ncbi.nlm.nih.gov/?term=Yang+Z&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Jinqiu Yuan](https://pubmed.ncbi.nlm.nih.gov/?term=Yuan+J&cauthor_id=42655935)[ 3 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-3 "Clinical Research Center & Big Data Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China."), [Xiaodan Huang](https://pubmed.ncbi.nlm.nih.gov/?term=Huang+X&cauthor_id=42655935)[ 4 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-4 "State Key Laboratory of Oncology in South China, Department of Radiation Oncology, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China."), [Xiaofang Liu](https://pubmed.ncbi.nlm.nih.gov/?term=Liu+X&cauthor_id=42655935)[ 5 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-5 "Institute of Robotics and Automatic Information Systems, College of Artificial Intelligence, Nankai University, Tianjin, China."), [Han Wang](https://pubmed.ncbi.nlm.nih.gov/?term=Wang+H&cauthor_id=42655935)[ 6 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-6 "Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China."), [Jonathan Poon](https://pubmed.ncbi.nlm.nih.gov/?term=Poon+J&cauthor_id=42655935)[ 7 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-7 "Information Technology and Health Informatics Division, Hospital Authority, Hong Kong SAR, China."), [Qi Dou](https://pubmed.ncbi.nlm.nih.gov/?term=Dou+Q&cauthor_id=42655935)[ 8 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-8 "Department of Computer Science and Engineering, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China."), [Arthur Sung](https://pubmed.ncbi.nlm.nih.gov/?term=Sung+A&cauthor_id=42655935)[ 9 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-9 "Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA."), [Martin C S Wong](https://pubmed.ncbi.nlm.nih.gov/?term=Wong+MCS&cauthor_id=42655935)[ 1 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-1 "The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.")[ 2 ](https://pubmed.ncbi.nlm.nih.gov/42655935/#short-view-affiliation-2 "Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.") ### Affiliations * 1 The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. * 2 Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. * 3 Clinical Research Center & Big Data Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, China. * 4 State Key Laboratory of Oncology in South China, Department of Radiation Oncology, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China. * 5 Institute of Robotics and Automatic Information Systems, College of Artificial Intelligence, Nankai University, Tianjin, China. * 6 Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
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