---
title: "Telehealth platforms prescribing off-label GLP-1s for addiction as FDA trials advance"
id: "stat-news-2-stat-telehealth-leapfrogs-fda-approval-with-off-label-glp-1-prescriptions-for"
canonical_url: "https://medichelpline.com/clinical-feed/stat-news-2-stat-telehealth-leapfrogs-fda-approval-with-off-label-glp-1-prescriptions-for"
content_type: "clinical_feed_article"
specialty: "Pharmacology"
source_name: "STAT News"
source_url: "https://www.statnews.com/2026/10/22/glp-1-drugs-substance-use-disorder-telehealth-off-label-prescription/?utm_campaign=rss"
published_at: "2026-10-22T08:30:00.000Z"
evidence_level: "Verified Feed"
license: "CC-BY-NC-4.0 / Informational Use"
---
# Telehealth platforms prescribing off-label GLP-1s for addiction as FDA trials advance
## Provenance & Clinical Metadata
- **Canonical URL:** https://medichelpline.com/clinical-feed/stat-news-2-stat-telehealth-leapfrogs-fda-approval-with-off-label-glp-1-prescriptions-for
- **Specialty:** [Pharmacology](https://medichelpline.com/clinical-feed/pharmacology.md)
- **Primary Source:** STAT News
- **Source URL:** [Original Journal Publication](https://www.statnews.com/2026/10/22/glp-1-drugs-substance-use-disorder-telehealth-off-label-prescription/?utm_campaign=rss)
- **Published At:** 2026-10-22T08:30:00.000Z
- **Evidence Rating:** Verified Feed
## Executive GIST (TL;DR)
- Telehealth companies have begun marketing **off-label** prescriptions of **GLP-1s** to treat **alcohol use disorder** and other substance use disorders, using both branded and compounded formulations. - Investigational programs from industry include Eli Lilly’s compound **brenipatide**, Altimmune’s **pemvidutide**, and a GLP-1 program at Baseline Therapeutics targeting alcohol, cocaine, and methamphetamine use disorders; these development efforts suggest a growing clinical interest in GLP-1 receptor agonists for addiction. - Photo caption in the source noted a treatment center had prescribed GLP-1s to more than 650 patients with substance use disorders, indicating early clinical uptake outside trials. - The article reported that addiction specialists view FDA approval for a new alcohol medication as possible in the near term — the first approval for alcohol use disorder in two decades — but did not provide timing or trial endpoints. - The source observed that online platforms may be shifting the burden of vetting unapproved uses onto patients, a concern among observers about safety, efficacy, and informed consent in teleprescribing. - The source did not report randomized trial results, dosing regimens, safety data, or long-term outcome measures for GLP-1 use in substance use disorders; those details remain unavailable in the provided text. - The remainder of the STAT News article was behind the STAT+ paywall and therefore not available in the provided source extract.
## Clinical Analysis & Structured Key Points
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Test your knowledge with our new weekday mini crossword [ Start solving ](https://www.statnews.com/stat-mini-crossword/) [STAT Plus](https://www.statnews.com/stat-plus/)[Health tech](https://www.statnews.com/category/health-tech/) # Telehealth leapfrogs FDA approval with off-label GLP-1 prescriptions for addiction ## Online platforms, experts say, can shift the burden of vetting unapproved drugs on to patients * [Manage alerts for this article](https://www.statnews.com/my-account/edit/#emails) * [Save this story for later](https://www.statnews.com/my-account/saved/) * [Share this article](https://www.statnews.com/2026/10/22/glp-1-drugs-substance-use-disorder-telehealth-off-label-prescription/?utm_campaign=rss) ![](https://www.statnews.com/wp-content/uploads/2025/07/GLP1-48-645x645.jpg) GLP-1 prescriptions in a fridge at Caron Treatment Centers in Wernersville, Pa., where providers have prescribed GLP-1s to more than 650 patients with substance use disorders.Rachel Wisniewski for STAT ![](https://www.statnews.com/wp-content/uploads/2021/02/katie-p-avatar-small-80x80.png) By [Katie Palmer](https://www.statnews.com/staff/katie-palmer/) Oct. 22, 2026 Health Tech Correspondent ![](https://www.statnews.com/wp-content/uploads/2021/02/katie-p-avatar-small-80x80.png) [Katie Palmer](https://www.statnews.com/staff/katie-palmer/) 1. [](https://x.com/KatieMPalmer "X") katie.palmer@statnews.com Katie covers the impact of health technology on patients, clinicians, and businesses. Her stories explore the price tag of clinical AI, digital health at the FDA, and the boom in direct-to-consumer telehealth. Confidential tips can be sent on Signal at palmer.01. For the popular diabetes and obesity medications known as GLP-1s, addiction medicine is one of many possible promising next acts. Eli Lilly is investigating a new drug, brenipatide, and testing it in alcohol use disorder. A new company called Baseline Therapeutics is [studying](https://www.statnews.com/2026/01/27/biotech-news-glp-1-drug-for-addiction-startup/) a GLP-1 receptor agonist in alcohol, cocaine, and methamphetamine use disorders; Altimmune is testing one called [pemvidutide](https://ir.altimmune.com/news-releases/news-release-details/altimmune-announces-positive-topline-results-reclaim-phase-2) for alcohol. Addiction medicine specialists are hopeful that the Food and Drug Administration may soon approve a new medication for alcohol use disorder — the first in two decades. Advertisement But some telehealth platforms that specialize in treating addiction aren’t waiting. In the last year, a few companies have begun to market [off-label prescriptions](https://www.fda.gov/patients/learn-about-expanded-access-and-other-treatment-options/understanding-unapproved-use-approved-drugs-label) of GLP-1s, both branded and compounded, to treat alcohol use disorder and other addictions. [![STAT+](https://www.statnews.com/wp-content/themes/stat/images/stat-plus-logo.svg)](https://www.statnews.com/stat-plus/) To read the rest of this story subscribe to STAT+. [Subscribe](https://www.statnews.com/stat-plus/) [Log In](https://www.statnews.com/login/) [addiction](https://www.statnews.com/topic/addiction/), [health tech](https://www.statnews.com/topic/health-tech/), [patients](https://www.statnews.com/topic/patients/), [STAT+](https://www.statnews.com/topic/stat-plus/), [Telehealth](https://www.statnews.com/topic/telehealth/) [Submit a correction request](https://www.statnews.com/contact/?how_can_we_help_=Editorial%20Correction%20Request)[Reprints](https://www.parsintl.com/publications/stat/) 1. ![](https://www.statnews.com/wp-content/uploads/2021/02/katie-p-avatar-small-80x80.png) [Katie Palmer](https://www.statnews.com/staff/katie-palmer/) 1. [](https://x.com/KatieMPalmer "X") 2. Health Tech Correspondent 1. [](https://x.com/KatieMPalmer "X") 2. Katie covers the impact of health technology on patients, clinicians, and businesses. 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