Introduction Diabetes mellitus is a global epidemic affecting hundreds of millions of people worldwide. The diabetic foot is among the most serious complications, and it is estimated that between 15 and 25% of patients with diabetes mellitus develop ulcers during their lifetime.
The costs for the treatments of foot ulcerations are enormous, and thus prevention and early personalised treatments are a priority. Many traditional clinical and metabolic analyses have been performed, but these should now be supported by modern specific multi-instrumental measurements.
Methods and analysis This is a no-profit, multicentre national study aimed at the prevention of complications in the diabetic foot. It is an interventional clinical trial, without medications or medical devices, involving two populations of patients with diabetes mellitus type-2.
BMJ Open published a clinical update in Research Highlights on 19 Jun 2026.
The item focuses on Multifactorial strategies for the prevention of the risks of ulceration in patients affected by diabetic foot: a no-profit, multicentre, clinical trial protocol.
Review the original article for the full source wording and details.