Study of CAR-T Therapy in Older Patients

Clinical Editorial

Official title: Observational Study of Commercial Chimeric Antigen Receptor T-cell (CAR T) Therapy in Older Patients With Hematologic Malignancies and With an Embedded Pilot Study of Longitudinal Geriatric and Neurocognitive Evaluation

Summary: This study is being done to find out how older patients respond to CAR-T cell therapy and how the treatment affects their quality of life. This is a quality of life study and participating in the study does not involve receiving any treatment, other than the standard treatment for participants' disease.

Conditions: Lymphoma, Refractory B-Cell Lymphoma, Lymphoma, B-Cell, DLBCL NOS, High-grade B-cell Lymphoma, Multiple Myeloma

Keywords: Lymphoma, CART therapy, relapsed refractory large B-cell lymphoma, High-grade B-cell Lymphoma, DLBCL NOS, Refractory B-Cell Lymphoma, 19-452, Memorial Sloan Kettering Cancer Center

Study type: OBSERVATIONAL

Enrollment: 154 (ESTIMATED)

Status: RECRUITING

Completion: 2027-03-04 (ESTIMATED)

Source Reference

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DOI

NCT04300998

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