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During 2019–2021, the Republic of the Marshall Islands experienced a dengue outbreak involving 1,908 cases. Environmental sanitation helped stop transmission on Ebeye island, but transmission continued for >1 year on Majuro atoll.
The Pacific region urgently needs to develop vector control capacity to address future dengue outbreaks. Dengue, caused by dengue virus (DENV), is a vectorborne disease transmitted by Aedes spp.
mosquitoes. DENV has 4 major serotypes (1–4); infection with one serotype protects against future infection with that serotype but leads to antibody-dependent enhancement and potentially more severe disease upon infection with a heterologous serotype ( 1 ).
The primary global dengue vector is the Ae. aegypti mosquito, which has a widespread and ever-expanding range ( 2 ).
In the Western Pacific, Ae. albopictus , Ae.
polynesiensis , and Ae. hensili dengue vectors coexist with Ae.
aegypti ( 3 ).
CDC Emerging Infectious Diseases Journal published a clinical update in Infectious Disease on 09 Apr 2026.
The item focuses on Outbreak of Dengue Virus Serotype 3, Republic of the Marshall Islands, 2019–2021.
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