If you look up transthyretin amyloid cardiomyopathy (ATTR-CM), you’ll read that the vast majority (an estimated 70% to 80%) of people living with this progressive heart condition are men . But experts increasingly believe that women develop ATTR-CM more often than we realize.
“ATTR-CM is not only seen in men — we should also suspect it in women,” says cardiologist Andres Carmona Rubio, MD . Dr.
Rubio and cardiologist Amanda Vest, MBBS , explain why this condition may be overlooked in women — and what you can do to make sure you get the right diagnosis. How it’s different for women In many ways, ATTR-CM looks similar in women and men — but they may be easier to miss in women.
There are several reasons why, including these. Limited research on ATTR-CM in women Women are underrepresented in all cardiology research , including studies on how common certain types of heart disease are.
So, Dr. Vest says it’s likely that more women have ATTR-CM than the stats suggest.
And that problem can snowball.
Cleveland Clinic Health Essentials published a clinical update in Research Highlights on 06 Apr 2026.
The item focuses on ATTR-CM Affects Women, Too.
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