Official title: A Prospective, Multicenter, Open-Label, Randomized Controlled Study of Early Intensive Lipid-Lowering in Endovascular Treatment for Acute Ischemic Stroke Summary: A prospective, multicenter, open-label, randomized controlled study to assess the effects of early intensive lipid-lowering initiated before endovascular treatment setting on (i) functional outcome in patients with acute ischemic stroke between preoperative intensive lipid-lowering therapy with PCSK9 inhibitor (PCSK9i) and guideline-recommended standard of care (SoC)(ii) safety in these patients. Conditions: Stroke Keywords: acute ischemic stroke, LDL-Cholersterol lowering, Endovascular Therapy, PCSK9, clinical trials Study type: INTERVENTIONAL Primary purpose: TREATMENT Phases: PHASE3 Enrollment: 652 (ESTIMATED) Status: RECRUITING Completion: 2029-01-01 (ESTIMATED)
ClinicalTrials.gov published a clinical update in Critical Care on 21 Jan 2026.
The item focuses on Early Aggressive Strategy for Treatment of Lipid-Lowering in Acute Ischemic Stroke Delivered With Endovascular Therapy for Large Artery Occlusion.
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