Official title: Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure Summary: The main objective of the study is to determine whether a subnormal serum creatinine value upon admission to the Post-ICU Care Unit predicts the need for prolonged ventilatory support. A parallel objective of the study is to determine whether exogenous in-take of the dietary supplement creatine in patients with subnormal serum creatinine value is associated with a shortened duration of ventilatory support and improved patients outcome. Conditions: Prolonged Mechanical Ventilation, Critical Illness Keywords: Prolonged mechanical ventilation, Critical illness, Creatinine, Creatine supplementation Study type: INTERVENTIONAL Primary purpose: TREATMENT Phases: NA Enrollment: 492 (ESTIMATED) Status: RECRUITING Completion: 2028-02-02 (ESTIMATED)
ClinicalTrials.gov published a clinical update in Critical Care on 05 Feb 2026.
The item focuses on Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure.
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