Official title: A Prospective, Multicenter, Open-Label, Randomized Controlled Study of Early Intensive Lipid-Lowering in Endovascular Treatment for Acute Ischemic Stroke Summary: A prospective, multicenter, open-label, randomized controlled study to assess the effects of early intensive lipid-lowering initiated before endovascular treatment setting on (i) functional outcome in patients with acute ischemic stroke between preoperative intensive lipid-lowering therapy with PCSK9 inhibitor (PCSK9i) and guideline-recommended standard of care (SoC)(ii) safety in these patients. Conditions: Stroke Keywords: acute ischemic stroke, LDL-Cholersterol lowering, Endovascular Therapy, PCSK9, clinical trials Study type: INTERVENTIONAL Primary purpose: TREATMENT Phases: PHASE3 Enrollment: 652 (ESTIMATED) Status: RECRUITING Completion: 2029-01-01 (ESTIMATED)
Official title: A Prospective, Multicenter, Open-Label, Randomized Controlled Study of Early Intensive Lipid-Lowering in Endovascular Treatment for Acute Ischemic Stroke
Summary: A prospective, multicenter, open-label, randomized controlled study to assess the effects of early intensive lipid-lowering initiated before endovascular treatment setting on (i) functional outcome in patients with acute ischemic stroke between preoperative intensive lipid-lowering therapy with PCSK9 inhibitor (PCSK9i) and guideline-recommended standard of care (SoC)(ii) safety in these patients.
Conditions: Stroke
Keywords: acute ischemic stroke, LDL-Cholersterol lowering, Endovascular Therapy, PCSK9, clinical trials
Study type: INTERVENTIONAL
Primary purpose: TREATMENT
Phases: PHASE3
Enrollment: 652 (ESTIMATED)
Status: RECRUITING
Completion: 2029-01-01 (ESTIMATED)