The PubMed entry documents a review article titled Fluid balance in critical illness: From arbitrary thresholds to outcome-linked stewardship. The title indicates a thematic focus on how clinicians manage fluid balance in patients with critical illness, proposing a conceptual transition away from rigid numeric thresholds toward strategies that link fluid management to patient-centered outcomes.
The PubMed record contains bibliographic metadata but does not include an abstract or the article text. As a result, specific study content, evidence synthesis, proposed stewardship frameworks, or clinical recommendations that the authors may present are not reported in this source.
The paper lists two authors:
Carmine Zoccali — affiliated with the Renal Research Institute (New York, USA), the Institute of Molecular Biology and Genetics (Biogem, Ariano Irpino, Italy), and Associazione Ipertensione Nefrologia Trapianto Renale (IPNET), Reggio Calabria, Italy. The PubMed record provides an electronic contact address for this author.
Francesca Mallamaci — affiliated with Associazione Ipertensione Nefrologia Trapianto Renale (IPNET), Reggio Calabria, Italy.
These affiliations indicate contributions from renal research and nephrology-associated institutions, reflecting the renal and fluid-management expertise relevant to the article's topic.
The article is indexed in European Journal of Internal Medicine (Eur J Intern Med) and listed as online ahead of print with a publication date of 2026 Aug 22. Persistent identifiers supplied in the PubMed record are:
These identifiers can be used to retrieve the full text from the publisher or library resources where available.
The PubMed entry lists the following keywords: Epidemiology; General medicine; Infectious diseases; Intensive care. These keywords suggest that the article addresses the clinical and epidemiological dimensions of fluid management across general medicine and intensive care settings, likely including relevance to infectious disease contexts where fluid resuscitation and balance are frequently managed.
The title and keyword set together imply a multidisciplinary perspective covering:
However, the PubMed record does not provide the article body, so the extent and specifics of coverage under these domains cannot be confirmed from this source alone.
The PubMed record explicitly notes that no abstract is available. Therefore, the following items are not reported in this source and cannot be summarized here:
Because these core elements are absent from the PubMed metadata, readers should access the full text via the DOI, the journal's website, institutional subscriptions, or library services to obtain the complete content and evidence presented by the authors.
The PubMed record includes a conflict of interest declaration: the authors state they have no competing interests regarding the content of the review. This declaration is reported in the article metadata and applies to the version indexed in PubMed.
Note on interpretation and next steps
The article title signals an important conceptual emphasis for clinicians caring for critically ill patients—moving from fixed fluid thresholds toward outcome-oriented stewardship of fluid therapy. However, because the PubMed entry lacks the abstract and body text, clinicians and researchers should consult the full article (using the DOI or journal access) to review the authors' evidence base, conclusions, and any practical recommendations before applying them in clinical practice.
For retrieval: use DOI 10.1016/j.ejim.2026.107141 or PMID 42629261 to locate the full text in Eur J Intern Med or through institutional/library access. The PubMed entry provides author contact information for the corresponding author, which may assist in requesting further details if full-text access is restricted.