Endocrine Society member, Daniel Hochbaum, MD, has received a Pershing Square Foundation Award “MIND” Prize, which includes a $750,000, three year grant. Hochbaum, an assistant professor in the Program in Neuroscience at Harvard Medical School and Beth Israel Deaconess Medical Center .
He is investigating how age-related declines in thyroid hormone signaling in the brain may contribute to cognitive decline and Alzheimer’s disease. His project will define how inflammation disrupts local production of the active thyroid hormone T3 and test whether restoring brain T3 signaling can rescue synaptic and behavioral deficits in Alzheimer’s models, potentially revealing a new endocrine-based strategy to slow neurodegeneration.
Hochbaum, one of eight recipients of the “MIND” Prize, is also scheduled to speak at ENDO 2026 in Chicago, Ill., in June. On Sunday June 14, he will be a part of the session entitled “Thyroid Hormone on the Brain,” which begins at 10:30 a.m.
Endocrine News published a clinical update in Research Highlights on 11 Mar 2026.
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