Extract Hypoglossal nerve stimulation (HGNS) continues to gain clinical momentum, with >100 000 Inspire implants worldwide and US Food and Drug Administration approval of a second system, Nyxoah's Genio implant last month following successful trial results [1]. Despite this momentum, efficacy remains suboptimal, with up to 50% of implanted real-world patients demonstrating inadequate response [2 - 4]. Hence, pre-operative "predictors" of success continue to tantalise clinicians and researchers alike.
European Respiratory Journal published a clinical update in Critical Care on 12 Mar 2026.
The item focuses on More correlates - not predictors - of hypoglossal nerve stimulation effectiveness.
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