For decades, induction and maintenance intravesical therapy with bacillus Calmette-Guérin (BCG) has served as the foundation for management of high-risk non–muscle invasive bladder cancer (NMIBC) [1]. In this issue of European Urology, two trials challenge that paradigm and introduce unique approaches that include treatment de-escalation for select patients and a novel protocol requiring fewer doses of BCG.
European Urology published a clinical update in Research Highlights on 24 Feb 2026.
The item focuses on Less Is More?
How Much Bacillus Calmette-Guérin (BCG) Is Enough for BCG-naïve High-risk Non–muscle invasive Bladder Cancer?.
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