We report a case of a 67-year-old man with rheumatoid arthritis (RA) presenting with symmetrical annular plaques confined to the face. Histopathology demonstrated dense dermal eosinophilia without flame figures, consistent with eosinophilic annular erythema (EAE).
Unlike the typical truncal distribution, lesions were limited to the face, a presentation reported in approximately 3% of cases. The patient was successfully treated with tofacitinib, a Janus kinase (JAK) inhibitor.
This report illustrates a rare facial variant of EAE and supports the efficacy of JAK inhibition in patients with concurrent RA.
Frontiers in Immunology published a clinical update in Infectious Disease on 20 Apr 2026.
The item focuses on Case Report: Facial-limited eosinophilic annular erythema in a patient with rheumatoid arthritis: successful treatment with tofacitinib.
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