Ablating the immune sensor STING in CAR-T cells enhances their effectiveness against pancreatic cancer when combined with a STING-activating drug that boosts immune responses in the tumor environment.
Gastroenterology (AGA) published a clinical update in Research Highlights on 13 Feb 2026.
The item focuses on Stimulator of Interferon Genes Ablation in T Cells Is Required for the Efficacy of Stimulator of Interferon Genes Agonists in Chimeric Antigen Receptor-T Cell Immunotherapy of Pancreatic Cancer.
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