This Author Correction relates to the SCREESCO randomized controlled trial comparing colonoscopy and fecal immunochemical testing (FIT) against usual care for diagnostic colorectal cancer (CRC) screening. The Correction, published in Nature Medicine on 10 September 2026, amends numerical confidence-interval data reported in the original article that was published online on 20 February 2026 (DOI: 10.1038/s41591-026-04225-9).
The notice states that an incorrect set of 95% confidence intervals was included in the first paragraph of the section titled “Diagnostic yield of screening and usual care.” The Correction replaces those intervals with revised 95% CIs for the cumulative incidence proportions of CRC at the end of follow-up in each trial arm. The publishers updated both the HTML and PDF versions of the article to reflect the corrected numbers.
The Correction provides the corrected cumulative incidence proportions for CRC and their 95% confidence intervals for the four trial groups. The updated values are reported as follows:
Primary colonoscopy arm: 0.69% (95% CI: 0.56–0.81%)
Control arm (for the colonoscopy comparison): 0.72% (95% CI: 0.66–0.78%)
FIT×2 arm: 0.61% (95% CI: 0.54–0.68%)
FIT×2 control arm: 0.73% (95% CI: 0.67–0.79%)
These corrected ranges replace the previously reported intervals in the specified paragraph. The Correction notice does not report any other numerical or textual changes beyond these confidence-interval updates.
The original research article that the Correction amends was published online 20 February 2026 and is identified by DOI 10.1038/s41591-026-04225-9. The Correction itself is published as a separate Author Correction entry in Nature Medicine with a version of record dated 10 September 2026. The journal entry notes that the Amendment was made to the HTML and PDF files of the original article.
Both the Correction and the underlying article are available under an Open Access arrangement. The Correction text includes a statement that the article is licensed under a Creative Commons Attribution 4.0 International License, permitting use, sharing, adaptation, distribution and reproduction with appropriate credit and licence attribution.
The Correction lists the article authors and their institutional affiliations as provided in the Author Information section. The author list includes Marcus Westerberg, Jonas F. Ludvigsson, Chris Metcalfe, Ulf Strömberg, Johannes Blom, Lars Engstrand, Mikael Hellström, Christian Löwbeer, Robert Steele, Lars Holmberg, Anna Forsberg and others.
Affiliations reported in the Correction span multiple departments and institutions, including but not limited to: the Department of Surgical Sciences at Uppsala University; the Department of Medical Epidemiology and Biostatistics and other units at Karolinska Institutet; Population Health Sciences at the University of Bristol; Sahlgrenska Academy at University of Gothenburg; and institutions in the UK such as the University of Dundee and King’s College London. The Correction identifies Marcus Westerberg as the corresponding author.
The Correction specifies that the amended sentence appears in the first paragraph of the “Diagnostic yield of screening and usual care” section of the original article. The publisher confirms the corrected sentence is now present in both the HTML and PDF versions of the paper.
The Correction repeats the journal’s Open Access licensing details: the article is distributed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). The notice includes standard rights and permissions language explaining reuse, attribution and circumstances under which additional permission may be required for third-party material.
Note: This rewrite is based exclusively on the content of the published Correction notice. No additional study details, numerical analyses beyond the corrected cumulative incidence proportions and 95% confidence intervals, or changes to methods or conclusions were reported in the Correction text provided.