RECRUITING · INTERVENTIONAL · TREATMENT study · Kidney Transplant · Phase 2 · Enrollment 200 · Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Official title: Advancing Transplantation Outcomes in Children (CTOT-41)
Summary: This is a pediatric kidney transplant study comparing the safety and efficacy of an immunosuppressive regimen of belatacept and sirolimus to tacrolimus and Mycophenolate Mofetil (MMF). Two hundred participants will be randomized (1:1) to one of two groups within 24 hours following the transplant procedure. The duration of the study from time of transplant to the primary endpoint is 12-24 months.
Conditions: Kidney Transplant
Keywords: kidney transplant, belatacept, sirolimus
Study type: INTERVENTIONAL
Primary purpose: TREATMENT
Phases: PHASE2
Enrollment: 200 (ESTIMATED)
Status: RECRUITING
Completion: 2028-06-30 (ESTIMATED)