Official title: Are Long Term Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)? Summary: The principal objective of this study is to compare the incidence of ventriculostomy related infections (VRIs) in patients who receive twenty-four hours of antibiotics, beginning no more than sixty minutes prior to EVD placement, to the incidence of VRIs in patients who also receive a pre-procedural dose of antibiotics with continued dosing of antibiotics for the duration of the external ventricular drain (EVD). At this time, the duration of prophylactic antibiotic use with antibiotic impregnated EVDs is unknown. Conditions: Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Ventriculitis, Cerebral, Hydrocephalus Keywords: Subarachnoid hemorrhage, Intracerebral Hemorrhage, Ventriculitis, Hydrocephalus Study type: INTERVENTIONAL Primary purpose: TREATMENT Phases: PHASE1 Enrollment: 84 (ESTIMATED) Status: RECRUITING Completion: 2026-06 (ESTIMATED)
Official title: Are Long Term Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?
Summary: The principal objective of this study is to compare the incidence of ventriculostomy related infections (VRIs) in patients who receive twenty-four hours of antibiotics, beginning no more than sixty minutes prior to EVD placement, to the incidence of VRIs in patients who also receive a pre-procedural dose of antibiotics with continued dosing of antibiotics for the duration of the external ventricular drain (EVD). At this time, the duration of prophylactic antibiotic use with antibiotic impregnated EVDs is unknown.
Conditions: Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Ventriculitis, Cerebral, Hydrocephalus
Keywords: Subarachnoid hemorrhage, Intracerebral Hemorrhage, Ventriculitis, Hydrocephalus
Study type: INTERVENTIONAL
Primary purpose: TREATMENT
Phases: PHASE1
Enrollment: 84 (ESTIMATED)
Status: RECRUITING
Completion: 2026-06 (ESTIMATED)