Hepatic stellate cells (HSCs) are activated during cholestasis. However, beyond liver fibrosis, whether HSCs influence bile acid (BA) synthesis and homeostasis remain largely unknown. This study investigates the role of activated HSCs (aHSCs) in the regulation of hepatic BA metabolism.
Journal of Hepatology published a clinical update in Research Highlights on 26 Mar 2026.
The item focuses on Activated hepatic stellate cells maintain liver bile acid homeostasis through paracrine FGF10/FGFR2 signaling.
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