Liver regeneration is a tightly regulated process requiring coordinated interactions between hepatocytes and non-parenchymal cells; however, its molecular mechanisms remain incompletely defined. Here, we aimed to investigate the role of interferon-related developmental regulator 1 (IFRD1) in regulating metabolic–immune crosstalk during liver regeneration.
Journal of Hepatology published a clinical update in Research Highlights on 17 Mar 2026.
The item focuses on IFRD1 orchestrates hepatocyte metabolism and macrophage interactions to facilitate liver regeneration.
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