Hepatocellular carcinoma (HCC) is the third deadliest cancer worldwide. Over 75% of HCC cases are associated with chronic viral infections. Mechanistic studies and preclinical therapeutic development for virus-associated HCC have been limited by a paucity of small animal models of chronic hepatotropic virus infection that faithfully recapitulate human disease.
Journal of Hepatology published a clinical update in Research Highlights on 11 Mar 2026.
The item focuses on An immunocompetent murine model of virus-elicited liver fibrosis and hepatocellular carcinoma.
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