Weight loss is the cornerstone of therapy for metabolic dysfunction-associated steatotic liver disease (MASLD). However, the optimal dietary approach for reducing intrahepatic triglycerides (IHTG) and the mechanisms underlying steatosis resolution remain poorly defined. We investigated whether weight loss via a ketogenic diet (KD) compared with a non-ketogenic diet (ND) differentially affects IHTG content, hepatic mitochondrial metabolism, and the circulating metabolome.
Journal of Hepatology published a clinical update in Research Highlights on 06 Feb 2026.
The item focuses on Distinct effects of ketogenic and non-ketogenic weight-loss diets on hepatic steatosis and mitochondrial metabolism in MASLD.
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