The eastern woodchuck (Marmota monax), which can be naturally infected with woodchuck hepatitis virus (WHV), has served as a model for studying aspects of human HBV infection, including the establishment of chronic infection and progression from chronic hepatitis to liver cancer. However, the cellular landscape of the woodchuck liver and its parallels to HBV infection remain uncharacterized.
Journal of Hepatology published a clinical update in Research Highlights on 22 Jan 2026.
The item focuses on A single-cell atlas of the woodchuck liver reveals cellular programs conserved in human HBV infection.
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