Insomnia With Objective Short Sleep Duration Is Associated With Incident Cardiovascular and Cerebrovascular Disease: Evidence from the UK Biobank Data

Journal of the American Heart Association, Volume 15, Issue 11 , June 2, 2026. BackgroundThe aim of this study is to assess the longitudinal association of the insomnia with short sleep duration phenotype with cardiovascular disease (CVD) and cerebrovascular disease (CBVD) in the UK biobank using self‐reported insomnia and accelerometer‐measured habitual sleep duration.MethodsThe sample sizes for incident CVD and CBVD were 6959 and 7690 participants, respectively, with an average follow‐up time of 3.6 years for CVD and 3.4 years for CBVD.

Short sleep duration was defined as a nightly sleep duration below the sample median (<7.3 hours) and insomnia as a self‐report of difficulty falling or staying asleep “Usually” versus Never/Rarely/Sometimes. Participants were classified into 4 mutually exclusive sleep groups based on the presence or absence of short sleep duration (Yes/No) and insomnia symptoms (Yes/No).