Membranous nephropathy (MN) in very elderly patients frequently remains antigen-negative after routine testing, limiting diagnostic precision. Recently, serine protease high temperature requirement protein A1 (HTRA1) has been identified as a novel MN autoantigen. Here, we focused on patients 80 years and older with MN and sought to systematically evaluate this association.
Kidney International published a clinical update in Research Highlights on 27 Mar 2026.
The item focuses on Serine Protease HTRA1 is a Common Autoantigen in Membranous Nephropathy in Patients of 80 Years and Older.
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