CKD patients continue to experience high cardiovascular risk despite advances in kidney disease management. The metabolic dysregulation characteristic of kidney disease, particularly in advanced stages, contributes to substantial uncertainty about the underlying mechanisms and how best to prevent or treat CV complications.
The article emphasizes the complexity of translating mechanistic insights into effective management, highlighting ongoing gaps in understanding rather than reporting specific data or outcomes. If data are incomplete in the source, note this uncertainty briefly.
Kidney International published a clinical update in Research Highlights on 18 Mar 2026.
The item focuses on From metaphor to mechanism: moving past the blind men’s elephant in cardiorenal-metabolic research.
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