The Hong Kong Genome Project established a genome sequencing database that provides improved diagnoses for patients and more efficient, population-tailored carrier status screening. Actionable pharmacogenomic variants were identified in almost all participants, informing drug prescriptions.
This work establishes a genomic resource and a transferable model for equitable precision medicine in underrepresented populations worldwide. Access to this article via Institution of Civil Engineers Library is not available.
Chan, S. H.
et al. Analysis of clinically relevant variants from ancestrally diverse Asian genomes.
Nat. Commun.
13 , 6694 (2022). This study from Singapore highlights the underrepresentation of Asian populations in human genomics research.
Chu, A. T.
& Chung, B. H.
Marketing and publicity strategies for launching the pilot phase of the Hong Kong Genome Project. J.
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Genom. 7 , 66–78 (2023).
The implementation and findings from the pilot phase of the HKGP. Gregg, A.
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Screening for autosomal recessive and X-linked conditions during pregnancy and preconception: a practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet.
Med. 23 , 1793–1806 (2021).
Miller, D. T.
Nature Medicine published a clinical update in Research Highlights on 12 Jun 2026.
The item focuses on The Hong Kong Genome Project is a flagship initiative for precision medicine in Chinese populations.
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