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Plasma Proteomic Signature Of The Human Menstrual Cycle

Large-scale analysis of nearly 3,000 plasma proteins across the menstrual cycle in over 2,700 women reveals proteomic patterns and a signature for predicting cycle phase.

GIST

Nature Medicine, Published online: 13 April 2026; doi:10.1038/s41591-026-04326-5 This Resource presents a large-scale analysis of nearly 3,000 circulating plasma proteins across the menstrual cycle in over 2,700 women from the UK Biobank, revealing distinct proteomic patterns across menstrual phases. This work sheds light on female reproductive biology and gynecological disorders, and provides a proteomic signature for accurate prediction of the menstrual cycle phase.

Clinical Editorial

Nature Medicine published a clinical update in Research Highlights on 13 Apr 2026. The item focuses on Plasma proteomic signature of the human menstrual cycle. Review the original article for the full source wording and details.

Original source: https://www.nature.com/articles/s41591-026-04326-5