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Live · 1,302 articles · Pharmacology · Updated 11:00 pm
The study reports that the metabolically activated proteostasis regulator **AA147** selectively reduces differentiation of pro-inflammatory **TH17** cells from naive CD4+ T cells. - AA147 was previous...
In vitro study evaluated **lacosamide** adsorption to three dialysis filter membranes (polysulfone **PS**, polyacrylonitrile **PAN**, and polyacrylonitrile polyethyleneimine **PAN-PEI**) and assessed...
This is a multicentre, **randomised controlled trial** comparing **liposuction** with conservative therapy for patients with **lipoedema** conducted in Germany and published in Lancet. - Publication d...
Pregnancy functions as a physiological stress test that can reveal latent cardiovascular vulnerability; **adverse pregnancy outcomes** (APOs) are markers of higher long-term cardiovascular morbidity a...
Moisture exposure by uniform vapor diffusion (no direct liquid contact) increased tablet mass by about **8.3 ± 0.77%**, demonstrating uptake without surface wetting. - A controlled dry-down following...
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The study reports a bioresponsive **Quject® gel** — a lyotropic liquid crystal system based on lecithin, Span 20, and tocopherol acetate — optimized to undergo an in situ sol–gel transition when expos...
Malaria remains a significant global health problem, particularly in children under five, and pediatric dosing often requires tablet fragmentation that increases bitterness and may reduce adherence. -...
The study reports successful transfer of a supercritical CO2-based **PGSS** (Particles from Gas-Saturated Solutions) liposome production process from laboratory to pilot scale, expanding reactor volum...
This study evaluated low-temperature hot-melt extrusion (HME) combined with fused deposition modeling (FDM) 3D printing to produce personalized immediate-release **glipizide (GPZ)** tablets, addressin...
The study developed a **multimodal convolutional neural network (MI-CNN)** to predict tablet-level dissolution profiles for immediate-release tablets using UV fluorescent images and compression force...
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