The authors analyzed uptake of maternal pertussis vaccination across a cohort of mothers whose children were born between January 2020 and March 2025. The dataset included 17,513 biological mothers drawn from a preventive Youth Health Care Center. Older mothers and employed mothers showed higher likelihood of receiving the vaccine. Reported odds ratios for higher maternal age ranged between 1.78 (95% CI 1.52–2.09) and 2.70 (95% CI 2.24–3.25), and employment was associated with an OR of 2.55 (95% CI 2.26–2.87). Short sentences: age and work mattered. Longer sentence: the study team thus identified demographic gradients in uptake, with socioeconomic markers such as employment and educational attainment forming distinct correlates of vaccine acceptance in this population.
The study captured reasons for non-vaccination beginning at the end of 2023, supplemented by retroactive recall to January 2023; this process yielded 768 reasons from 728 mothers. Most reasons did not map cleanly onto measured sociodemographic variables, the authors reported. One exception: women aged ≥41 were more likely to decline because of concerns about vaccination during pregnancy (OR 2.61, 95% CI 1.16–5.88). Short, direct statement: concerns about pregnancy safety were more common in older mothers. In a more detailed observation, the investigators found that language barriers affected informational access: mothers whose native language was not Dutch or English more often reported they did not receive the right information on time from healthcare workers, with ORs ranging between 2.19 (95% CI 1.10–4.34) and 2.96 (95% CI 1.19–7.37).
Records originated from a preventive Youth Health Care Center; the cohort comprised 17,513 biological mothers. The authors note that reason-capturing formally began at the end of 2023 and that they used retroactive recall to collect reasons back to January 2023. This dual approach produced 768 documented reasons reported by 728 mothers. The abstract specified logistic regression as the analytic method used to examine associations between sociodemographic factors, vaccine uptake, and reasons for non-receipt. The study did not report complete model covariates, detailed variable definitions, or temporal sequencing of information provision relative to vaccine offers in the abstract.
Higher maternal age and employment were consistently associated with increased MPV uptake. The reported OR range for age (1.78–2.70) indicates a graded relationship across age strata, according to the authors. Employment showed a strong positive association (OR 2.55). Conversely, lower educational attainment was associated with reduced uptake (OR 0.41, 95% CI 0.37–0.46), and parity was negatively associated with uptake (OR 0.61, 95% CI 0.55–0.68) — meaning mothers with higher parity were less likely to be vaccinated. The abstract also reports variable associations for mothers born outside the Netherlands; specific odds ratios varied by country or region of birth, but those precise stratified values were not detailed in the abstract beyond a statement that they differed.
Language emerged as a measurable factor tied to reasons for non-vaccination. Mothers whose native language was not Dutch or English more frequently reported that they did not receive timely or correct information from healthcare workers. Reported odds ratios for this association fell between 2.19 and 2.96. The authors also observed that most reasons for declining vaccination were not strongly patterned by the examined sociodemographic factors; this suggests that hesitancy drivers may crosscut demographic categories. Short sentence: reasons were heterogeneous. Longer sentence: while some demographic groups showed specific tendencies, the distribution of stated reasons implies that single-factor communication strategies may miss important subgroups.
The cohort design used administrative records and retrospective recall for reasons; the abstract explicitly states that reasons were recorded only from the end of 2023 with retroactive reporting to January 2023, which introduces potential recall bias. The abstract did not provide full logistic regression model specifications, a complete list of covariates, nor the timing and content of information given by healthcare workers relative to vaccine offers. The authors did not report in the abstract any intervention strategies to address the identified gaps. Short, concrete note to end on: the published abstract limits readers to the reported summary statistics and associations and does not contain granular methodological detail necessary to assess residual confounding, exact variable coding, or potential clustering by clinic. The study offers directions for targeted interventions to improve MPV uptake; the abstract did not set specific regulatory milestones or implementation timelines.