by Camilo Ramírez-Giraldo, Daniela Álvarez-León, Alejandro Karduss-López, on behalf of Bogotá Task Force Collaboration Group Background Laparoscopic cholecystectomy is one of the most frequently performed operations worldwide and the standard treatment for benign gallbladder disease. Although several “safe cholecystectomy” initiatives aim to prevent bile duct injury, current guidelines do not comprehensively address the intraoperative technical conduct of the procedure.
Key elements—including exposure, dissection techniques, technical sequencing, and intraoperative decision-making—remain inconsistently defined. This protocol describes the development of an evidence-based, globally applicable clinical procedure guideline intended to standardize technical performance, enhance patient safety, and support surgical training and quality improvement.
Methods The guideline will be developed following AGREE II standards to ensure methodological rigor, transparency, and stakeholder involvement. The Guideline Development Group comprises coordinators, a steering committee, and multidisciplinary experts from surgical societies and academic institutions.
Clinical questions will be generated using the PICO framework and refined through a Delphi consensus process following the ACCORD guideline. For each question, systematic literature searches will be conducted in accordance with PRISMA standards.
PLOS ONE (Medicine) published a clinical update in Research Highlights on 29 May 2026.
The item focuses on Protocol for the development of a procedure guide on Laparoscopic Cholecystectomy: Beyond bile duct injury prevention.
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