Proceedings of the National Academy of Sciences, Volume 123, Issue 14, April 2026. SignificanceRibosomally synthesized and posttranslationally modified peptides (RiPPs) are a superfamily of natural products that display antibiotic, antifungal, anticancer, and metal-binding activities. Their biosynthesis typically follows a common logic ...
PNAS published a clinical update in Research Highlights on 30 Mar 2026.
The item focuses on Co-opting the bacterial lipoprotein pathway for the biosynthesis of lipidated macrocyclic peptides.
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